Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis

W Wen, C Chen, J Tang, C Wang, M Zhou… - Annals of …, 2022 - Taylor & Francis
Background The coronavirus disease (COVID-19) epidemic has not been completely
controlled. Although great achievements have been made in COVID-19 research and many …

[HTML][HTML] Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …

[HTML][HTML] Randomized trial of metformin, ivermectin, and fluvoxamine for Covid-19

CT Bramante, JD Huling, CJ Tignanelli… - … England Journal of …, 2022 - Mass Medical Soc
Background Early treatment to prevent severe coronavirus disease 2019 (Covid-19) is an
important component of the comprehensive response to the severe acute respiratory …

[HTML][HTML] Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

M Taquet, R Sillett, L Zhu, J Mendel… - The Lancet …, 2022 - thelancet.com
Background COVID-19 is associated with increased risks of neurological and psychiatric
sequelae in the weeks and months thereafter. How long these risks remain, whether they …

An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

[HTML][HTML] Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform …

G Reis, EA dos Santos Moreira-Silva… - The Lancet Global …, 2022 - thelancet.com
Background Recent evidence indicates a potential therapeutic role of fluvoxamine for
COVID-19. In the TOGETHER trial for acutely symptomatic patients with COVID-19, we …

Neurological manifestations of long-COVID syndrome: a narrative review

MI Stefanou, L Palaiodimou, E Bakola… - … advances in chronic …, 2022 - journals.sagepub.com
Accumulating evidence points toward a very high prevalence of prolonged neurological
symptoms among coronavirus disease 2019 (COVID-19) survivors. To date, there are no …

[HTML][HTML] Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

S Ramakrishnan, DV Nicolau, B Langford… - The Lancet …, 2021 - thelancet.com
Background Multiple early reports of patients admitted to hospital with COVID-19 showed
that patients with chronic respiratory disease were significantly under-represented in these …

[HTML][HTML] Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

[HTML][HTML] Host-directed immunotherapy of viral and bacterial infections: past, present and future

RS Wallis, A O'Garra, A Sher, A Wack - Nature Reviews Immunology, 2023 - nature.com
The advent of COVID-19 and the persistent threat of infectious diseases such as
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …