[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave

ST Tan, AT Kwan, I Rodríguez-Barraquer, BJ Singer… - Nature Medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infections in
vaccinated individuals and reinfections in previously infected individuals have become …

Resistance of Omicron subvariants BA. 2.75. 2, BA. 4.6, and BQ. 1.1 to neutralizing antibodies

D Planas, T Bruel, I Staropoli… - Nature …, 2023 - nature.com
Convergent evolution of SARS-CoV-2 Omicron BA. 2, BA. 4, and BA. 5 lineages has led to
the emergence of several new subvariants, including BA. 2.75. 2, BA. 4.6. and BQ. 1.1. The …

Accelerating antiviral drug discovery: lessons from COVID-19

A von Delft, MD Hall, AD Kwong, LA Purcell… - Nature Reviews Drug …, 2023 - nature.com
During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and
collaborative drug discovery efforts took place in academia and industry, culminating in …

Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort study

S Hakki, J Zhou, J Jonnerby… - The Lancet …, 2022 - thelancet.com
Background Knowledge of the window of SARS-CoV-2 infectiousness is crucial in
developing policies to curb transmission. Mathematical modelling based on scarce empirical …

Viral dynamics and duration of PCR positivity of the SARS-CoV-2 Omicron variant

JA Hay, SM Kissler, JR Fauver, C Mack, CG Tai… - MedRxiv, 2022 - medrxiv.org
Abstract Background The Omicron SARS-CoV-2 variant is responsible for a major wave of
COVID-19, with record case counts reflecting high transmissibility and escape from prior …

Effect of SARS-CoV-2 prior infection and mRNA vaccination on contagiousness and susceptibility to infection

D Mongin, N Bürgisser, G Laurie, G Schimmel… - Nature …, 2023 - nature.com
The immunity conferred by SARS-CoV-2 vaccines and infections reduces the transmission
of the virus. To answer how the effect of immunity is shared between a reduction of …

Analytical sensitivity of eight different SARS-CoV-2 antigen-detecting rapid tests for Omicron-BA. 1 variant

M Bekliz, K Adea, O Puhach… - Microbiology …, 2022 - Am Soc Microbiol
The emergence of each novel SARS-CoV-2 variant of concern (VOC) requires investigation
of its potential impact on the performance of diagnostic tests in use, including antigen …

SARS-CoV-2 Omicron BA. 1 and BA. 2 are attenuated in rhesus macaques as compared to Delta

N van Doremalen, M Singh, TA Saturday, CK Yinda… - Science …, 2022 - science.org
Since the emergence of SARS-CoV-2, five different variants of concern (VOCs) have been
identified: Alpha, Beta, Gamma, Delta, and Omicron. Because of confounding factors in the …