[HTML][HTML] Gender differences in the pathogenesis and risk factors of hepatocellular carcinoma

R Nevola, G Tortorella, V Rosato, L Rinaldi, S Imbriani… - Biology, 2023 - mdpi.com
Simple Summary Significant gender disparities have been highlighted in the incidence,
aggressiveness, and prognosis of HCC. A different epidemiological distribution of the risk …

[HTML][HTML] Neoadjuvant and adjuvant systemic therapies in loco-regional treatments for hepatocellular carcinoma: are we at the dawn of a new era?

R Nevola, A Delle Femine, V Rosato, LA Kondili… - Cancers, 2023 - mdpi.com
Simple Summary The treatment of hepatocellular carcinoma is burdened by an
unacceptable recurrence rate after loco-regional treatment. Unlike all other solid tumors, no …

Impact of surgical margin width on prognosis following resection of hepatocellular carcinoma varies on the basis of preoperative alpha-feto protein and tumor burden …

Y Endo, MM Munir, S Woldesenbet, E Katayama… - Annals of Surgical …, 2023 - Springer
Background We sought to examine the prognostic impact of margin width at time of
hepatocellular carcinoma (HCC) resection relative to the alpha-feto protein tumor burden …

[HTML][HTML] SART3, regulated by p53, is a biomarker for diagnosis, prognosis and immune infiltration in hepatocellular carcinoma

J Nong, K Yang, T Li, C Lan, X Zhou, J Liu, H Xie… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Objective: This study aimed to investigate the role of squamous cell carcinoma antigen
recognized by T cells 3 (SART3) in hepatocellular carcinoma (HCC). Methods: SART3 …

PIVKA‐II combined with tumor burden score to predict long‐term outcomes of AFP‐negative hepatocellular carcinoma patients after liver resection

Z Qiu, Y Wu, W Qi, C Li - Cancer Medicine, 2024 - Wiley Online Library
Background This study aimed to establish a simple prognostic scoring model based on
tumor burden score (TBS) and PIVKA‐II to predict long‐term outcomes of α‐fetoprotein …

[HTML][HTML] Identification of subclusters and prognostic genes based on glycolysis/gluconeogenesis in hepatocellular carcinoma

D Chen, A Aierken, H Li, R Chen, L Ren… - Frontiers in …, 2023 - frontiersin.org
Background This study aimed to examine glycolysis/gluconeogenesis-related genes in
hepatocellular carcinoma (HCC) and evaluate their potential roles in HCC progression and …

Clinical-Radiological Characteristic for Predicting Ultra-Early Recurrence After Liver Resection in Solitary Hepatocellular Carcinoma Patients

X Wang, Y Yu, Y Tao, Y Wang, C Zhang… - Journal of …, 2023 - Taylor & Francis
Objective This study aims to identify independent risk factors for ultra-early recurrence in
patients with early solitary hepatocellular carcinoma (HCC) and develop an individualized …

[HTML][HTML] Adjuvant therapy for hepatocellular carcinoma: Dilemmas at the start of a new era

JH Zhong - World Journal of Gastroenterology, 2024 - ncbi.nlm.nih.gov
Abstract Approximately 50%-70% of patients with hepatocellular carcinoma experience
recurrence within five years after curative hepatic resection or ablation. As a result, many …

SRSF7 is a promising prognostic biomarker in hepatocellular carcinoma and is associated with immune infiltration

W Shen, L Yuan, F Cheng, Z Wu, X Li - Genes & Genomics, 2024 - Springer
Background Previous studies indicate that the splicing process, regulated by the cellular
machinery of tumors (spliceosome), undergoes alterations, leading to oncogenic splicing …

[HTML][HTML] Advancements in Immunotherapeutic Treatments for Hepatocellular Carcinoma: Potential of Combination Therapies

Y Zarlashat, H Mushtaq, L Pham, W Abbas… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and a significant global
health burden, with increasing incidence rates and limited treatment options …