Recently, the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron
variant (B. 1.1. 529) was first identified in Botswana in November 2021. It was first reported …

The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

Despite notable scientific and medical advances, broader political, socioeconomic and
behavioural factors continue to undercut the response to the COVID-19 pandemic 1, 2. Here …

As of November 2021, several SARS‐CoV‐2 variants appeared and became dominant
epidemic strains in many countries, including five variants of concern (VOCs) Alpha, Beta …

Abstract The World Health Organizations declaration of the COVID-19 pandemic was a
milestone for the scientific community. The high transmission rate and the huge number of …

Abstract The Omicron (B. 1.1. 529) variant was first reported in South Africa and rapidly
spread worldwide in early November 2021. This caused panic in various countries, so it is …

The world has not yet completely overcome the fear of the havoc brought by SARS-CoV-2.
The virus has undergone several mutations since its initial appearance in China in …

Current COVID-19 vaccines are based on prototypic spike sequences from ancestral 2019
SARS-CoV-2 strains. However, the ongoing pandemic is fueled by variants of concern …

From December 2021 to May 2022, the Omicron BA. 1 and BA. 2 subvariants successively
became the most dominant strains in many countries around the world. Subsequently …

Coronavirus disease 2019 (COVID-19) has become a new public health crisis threatening
the world. Dysregulated immune responses are the most striking pathophysiological …