BACKGROUND The mammalian immune system is a remarkable sensory system for the
detection and neutralization of pathogens. History is replete with the devastating effects of …

Technological advancement, data democratisation, and decreasing costs have led to a
revolution in molecular biology in which the entire set of DNA, RNA, proteins, and various …

Importance Pharmacogenomic (PGx) testing provides preemptive pharmacotherapeutic
guidance regarding the lack of therapeutic benefit or adverse drug reactions of PGx targeted …

BACKGROUND Heart transplantation provides a significant improvement in survival and
quality of life for patients with end-stage heart disease, however many recipients experience …

BACKGROUND: The association between genetic polymorphisms and early cardiac
allograft vasculopathy (CAV) development is relatively unexplored. Identification of genes …

In this study we performed a next generation sequencing of 210 genes in 140 patients with
cardiac failure requiring a heart transplantation. We identified a total of 48 candidate variants …

Background Circulating cell-free deoxyribonucleic acid (cfDNA) is promptly materializing as
a highly useful tool for the surveillance of solid-organ transplant rejection. Donor-specific …

Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue disorders
comprised of several types. Classic EDS is an autosomal dominant disorder with stretchable …

La transplantation rénale est le meilleur traitement de suppléance pour l'insuffisance rénale
chronique terminale. Cependant, des défis majeurs liés au rejet et l'échec chronique restent …

It has been well appreciated in solid organ, composite tissue and cell transplantation that
HLA mismatches between donor and recipient are key contributors to the alloimmune …