Role of genetic architecture in phenotypic plasticity

P Kovuri, A Yadav, H Sinha - Trends in Genetics, 2023 - cell.com
Phenotypic plasticity, the ability of an organism to display different phenotypes across
environments, is widespread in nature. Plasticity aids survival in novel environments …

[HTML][HTML] Advances in the Discovery and Engineering of Gene Targets for Carotenoid Biosynthesis in Recombinant Strains

B Su, MR Deng, H Zhu - Biomolecules, 2023 - mdpi.com
Carotenoids are naturally occurring pigments that are abundant in the natural world. Due to
their excellent antioxidant attributes, carotenoids are widely utilized in various industries …

[HTML][HTML] Evolution of haploid and diploid populations reveals common, strong, and variable pleiotropic effects in non-home environments

V Chen, MS Johnson, L Hérissant, PT Humphrey… - Elife, 2023 - ncbi.nlm.nih.gov
Adaptation is driven by the selection for beneficial mutations that provide a fitness
advantage in the specific environment in which a population is evolving. However …

[HTML][HTML] Barcoding Populations of Pseudomonas fluorescens SBW25

L Theodosiou, AD Farr, PB Rainey - Journal of Molecular Evolution, 2023 - Springer
In recent years, evolutionary biologists have developed an increasing interest in the use of
barcoding strategies to study eco-evolutionary dynamics of lineages within evolving …

Far From Home: Evolution of haploid and diploid populations reveals common, strong, and variable pleiotropic effects in non-home environments

VK Chen, MS Johnson, L Hérissant, PT Humphrey… - bioRxiv, 2023 - biorxiv.org
Adaptation is driven by the selection for beneficial mutations that provide a fitness
advantage in the specific environment in which a population is evolving. However …

Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs across hundreds of fluconazole-resistant yeast strains

Schmidlin, Apodaca, Newell, Sastokas, Kinsler - bioRxiv, 2023 - biorxiv.org
There is growing interest in designing multidrug therapies that leverage tradeoffs to combat
drug resistance. Tradeoffs are common in evolution and occur when, for example, resistance …

[PDF][PDF] 過剰発現によりストレス環境への耐性を向上させる酵母遺伝子集団の性質に関する研究

N SAEKI - 2023 - ousar.lib.okayama-u.ac.jp
生体は, 内外の環境変化に応答して遺伝子発現量を緻密に制御する. この制御が適切に働くこと
により, 生体は様々な環境下でも増殖, 生存することができる. 従って, 制御から外れた遺伝子の過剰 …