Reprogramming of cellular metabolism is a hallmark of cancer. Mitochondrial ATP synthase
(MAS) produces most of the ATP that drives the cell. High expression of the MAS-composing …

Objectives The study of sex differences in hyperuricemia can provide not only a theoretical
basis for this clinical phenomenon but also new therapeutic targets for urate-lowering …

Abstract Objective ABCG2 rs2231142 (Q141K) has been reported to be associated with
poor response to allopurinol, while there are conflicting data on the association between the …

Glioblastoma multiforme (GBM) is the most fatal cancer among brain tumors, and the
standard treatment of GBM patients is surgical tumor resection followed by radiotherapy and …

Estrogen deficiency usually leads to bone loss and osteoporosis in postmenopausal
women. Osteoblasts play crucial roles in bone formation. However, osteoblast functions are …

Although it has gained more attention in recent years, the relationship between breast
cancer (BC) and mitochondrial oxidative phosphorylation (OXPHOS) is still not well …

Background The ABCG2 rs2231142 single nucleotide polymorphism (SNP) is one of the
most significant genetic variants associated with hyperuricemia (HUA) in Asian populations …

Background Tamoxifen resistance in breast cancer is an unsolved problem in clinical
practice. The aim of this study was to determine the potential mechanisms of tamoxifen …

Background Early prediction of response to neoadjuvant chemotherapy (NAC) is critical in
choosing appropriate chemotherapeutic regimen for patients with locally advanced breast …

Molecular heterogeneity has great significance in the disease biology of multiple myeloma
(MM). Thus, the analysis combined single-cell RNA-seq (scRNA-seq) and bulk RNA-seq …