Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors
AL Gavin, D Huang, TR Blane, TC Thinnes… - Nature …, 2021 - nature.com
Abstract Phospholipase D3 (PLD3) and PLD4 polymorphisms have been associated with
several important inflammatory diseases. Here, we show that PLD3 and PLD4 digest ssRNA …
several important inflammatory diseases. Here, we show that PLD3 and PLD4 digest ssRNA …
The clinical utility of CD163 in viral diseases
Macrophage activation and hypercytokinemia are notable presentations in certain viral
infections leading to severe disease and poor prognosis. Viral infections can cause …
infections leading to severe disease and poor prognosis. Viral infections can cause …
[HTML][HTML] Hemophagocytic syndrome and COVID-19: A comprehensive review
MM Fadlallah, SM Salman, MM Fadlallah, H Rahal - Cureus, 2023 - ncbi.nlm.nih.gov
Hemophagocytic lymphohistiocytosis (HLH), a hyperinflammatory hyperferritinemic
syndrome, is triggered by various etiologies and diseases and can lead to multiorgan …
syndrome, is triggered by various etiologies and diseases and can lead to multiorgan …
[HTML][HTML] COVID-19 complications in a newly diagnosed HIV patient: a case of multiple herpesvirus reactivation and HLH post-ART initiation
S Davari, PS Taunk, T Madaline - The American Journal of Case …, 2023 - ncbi.nlm.nih.gov
Objective: Rare coexistence of disease or pathology Background: Hemophagocytic
lymphohistiocytosis (HLH) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS …
lymphohistiocytosis (HLH) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS …
T cell receptor β repertoires in patients with COVID-19 reveal disease severity signatures
J Xu, X Li, N Yuan, C Li, J Yang, L Cheng, Z Lu… - Frontiers in …, 2023 - frontiersin.org
Background The immune responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are crucial in maintaining a delicate balance between protective effects and …
(SARS-CoV-2) are crucial in maintaining a delicate balance between protective effects and …
Lung expression of macrophage markers CD68 and CD163, angiotensin converting enzyme 2 (ACE2), and Caspase-3 in COVID-19
Background and Objectives: The coronavirus (SARS-CoV-2) damages all systems and
organs. Yet, to a greater extent, the lungs are particularly involved, due to the formation of …
organs. Yet, to a greater extent, the lungs are particularly involved, due to the formation of …
A hyperinflammation clinical risk tool, HI5-NEWS2, stratifies hospitalised COVID-19 patients to associate risk of death and effect of early dexamethasone in an …
Background The success of early dexamethasone therapy for hospitalised COVID-19 cases
in treatment of Sars-CoV-2 infection may predominantly reflect its anti-inflammatory action …
in treatment of Sars-CoV-2 infection may predominantly reflect its anti-inflammatory action …
Unraveling the Complexities of Severe Acute Respiratory Syndrome Coronavirus 2: A Comprehensive Ophthalmic and Systemic Perspective
The editorial explores the profound implications of the Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) pandemic, which emerged in December 2019 and rapidly …
Coronavirus 2 (SARS-CoV-2) pandemic, which emerged in December 2019 and rapidly …
Желтуха, одышка и гиперферритинемия у пациентки, перенесшей COVID-19
ВР Гречишникова, ПЕ Ткаченко, МС Жаркова… - Российский журнал …, 2022 - gastro-j.ru
Аннотация Цель представленного клинического наблюдения: продемонстрировать
необходимость включения в круг дифференциального диагноза гемофагоцитарного …
необходимость включения в круг дифференциального диагноза гемофагоцитарного …