[HTML][HTML] Hybrid fracture fixation systems developed for orthopaedic applications: A general review

L Tian, N Tang, T Ngai, C Wu, Y Ruan, L Huang… - Journal of orthopaedic …, 2019 - Elsevier
Orthopaedic implants are applied daily in our orthopaedic clinics for treatment of
musculoskeletal injuries, especially for bone fracture fixation. To realise the multiple …

Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis

Y Li, J Xu, J Mi, X He, Q Pan, L Zheng, H Zu, Z Chen… - Biomaterials, 2021 - Elsevier
Critical size bone defects are frequently caused by accidental trauma, oncologic surgery,
and infection. Distraction osteogenesis (DO) is a useful technique to promote the repair of …

Influence of low-magnitude high-frequency vibration on bone cells and bone regeneration

L Steppe, A Liedert, A Ignatius… - … in bioengineering and …, 2020 - frontiersin.org
Bone is a mechanosensitive tissue for which mechanical stimuli are crucial in maintaining its
structure and function. Bone cells react to their biomechanical environment by activating …

Dual modulation of bone formation and resorption with zoledronic acid-loaded biodegradable magnesium alloy implants improves osteoporotic fracture healing: An in …

G Li, L Zhang, L Wang, G Yuan, K Dai, J Pei, Y Hao - Acta biomaterialia, 2018 - Elsevier
Osteoporotic fracture (OPF) remains a major clinical challenge for skeletal regeneration.
Impaired osteogenesis and excessive remodeling result in prolonged and poor quality of …

[HTML][HTML] Osteoblastic and anti-osteoclastic activities of strontium-substituted silicocarnotite ceramics: In vitro and in vivo studies

J Zeng, J Guo, Z Sun, F Deng, C Ning, Y Xie - Bioactive materials, 2020 - Elsevier
Osteoporosis bone defect is a refractory orthopaedic disease which characterized by
impaired bone quality and bone regeneration capacity. Current therapies, including …

An innovative Mg/Ti hybrid fixation system developed for fracture fixation and healing enhancement at load-bearing skeletal site

L Tian, Y Sheng, L Huang, DHK Chow, WH Chau… - Biomaterials, 2018 - Elsevier
Magnesium (Mg) is a potential biomaterial suitable for developing biodegradable
orthopaedic implants, especially as internal fixators for fracture fixation at non-load bearing …

Effects of 18-month low-magnitude high-frequency vibration on fall rate and fracture risks in 710 community elderly—a cluster-randomized controlled trial

KS Leung, CY Li, YK Tse, TK Choy, PC Leung… - Osteoporosis …, 2014 - Springer
This study is a prospective cluster-randomized controlled clinical trial involving 710 elderly
subjects to investigate the long-term effects of low-magnitude high-frequency vibration …

[HTML][HTML] Biodegradable magnesium pins enhanced the healing of transverse patellar fracture in rabbits

DHK Chow, J Wang, P Wan, L Zheng, MTY Ong… - Bioactive materials, 2021 - Elsevier
Displaced fractures of patella often require open reduction surgery and internal fixation to
restore the extensor continuity and articular congruity. Fracture fixation with biodegradable …

[PDF][PDF] Vibration treatment modulates macrophage polarisation and enhances early inflammatory response in oestrogen-deficient osteoporotic-fracture healing

SK Chow, YN Chim, J Wang, N Zhang, RM Wong… - Eur Cell …, 2019 - ecmjournal.org
Fracture healing is a well-orchestrated and coordinated process and begins with the
inflammatory stage involving the infiltration of immune cells and the release of cytokines …

[PDF][PDF] The effect of whole body vibration on fracture healing-a systematic review

J Wang, KS Leung, SK Chow, WH Cheung - Eur Cell Mater, 2017 - ecmjournal.org
This systematic review examines the efficacy and safety of whole body vibration (WBV) on
fracture healing. A systematic literature search was conducted with relevant keywords in …