Cancer microenvironment is critical for tumorigenesis and cancer progression. The
extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells …

The extracellular matrix (ECM) is a complex, dynamic network present within all tissues and
organs that not only acts as a mechanical support and anchorage point but can also direct …

The tumor microenvironment (TME) is a complex macromolecular network filled with a series
of stromal cells. It plays an important role in tumorigenesis, development, immune escape …

Coronary artery bypass grafting (CABG) remains the most common procedure used in
cardiovascular surgery for the treatment of severe coronary atherosclerotic heart disease. In …

Avascular necrosis of the femoral head (ANFH) is a painful disorder characterized by the
cessation of blood supply to the femoral head, leading to its death and subsequent joint …

Immunotherapy has been recognized as an effective and important therapeutic modality for
multiple types of cancer. Nevertheless, it has been increasing recognized that clinical …

Tumor angiogenesis is critical for tumor metastasis by providing oxygen, nutrients, and
metastatic pathways. As a potential anti‐angiogenic agent, Dihydroartemisinin (DHA) can …

Circular RNAs (circRNAs) are a new series of noncoding RNAs (ncRNAs) that have been
reported to be expressed in eukaryotic cells and have a variety of biological functions in the …

Sprouting angiogenesis plays a key role during bone regeneration. For example, insufficient
early revascularization of the injured site can lead to delayed or non-healing. During …

Ocular neovascular disease (OND), characterized by the aberrant formation of immature
blood vessels, is the leading cause of vision impairment and blindness. It is important to find …