Molecular insights into regulatory RNAs in the cellular machinery

S Yang, SH Kim, E Yang, M Kang, JY Joo - Experimental & Molecular …, 2024 - nature.com
It is apparent that various functional units within the cellular machinery are derived from
RNAs. The evolution of sequencing techniques has resulted in significant insights into …

The adverse outcome pathway framework applied to neurological symptoms of COVID-19

HT Hogberg, A Lam, E Ohayon, MA Shahbaz… - Cells, 2022 - mdpi.com
Several reports have shown that the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has the potential to also be neurotropic. However, the mechanisms by which …

Conservation and enhanced binding of SARS-CoV-2 Omicron spike protein to coreceptor neuropilin-1 predicted by docking analysis

P Baindara, D Roy, SM Mandal, AG Schrum - Infectious Disease Reports, 2022 - mdpi.com
The Omicron variant of SARS-CoV-2 bears peptide sequence alterations that correlate with
a higher infectivity than was observed in the original SARS-CoV-2 isolated from Wuhan …

[HTML][HTML] Oxidative stress and COVID-19-associated neuronal dysfunction: mechanisms and therapeutic implications: SARS-CoV-2 (COVID-19)-mediated oxidative …

DR Bowen, S Pathak, RM Nadar… - Acta Biochimica et …, 2023 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome (SARS)-CoV-2 virus causes novel coronavirus disease
2019 (COVID-19), and there is a possible role for oxidative stress in the pathophysiology of …

Recent aspects of periodontitis and Alzheimer's disease—a narrative review

D Cichońska, M Mazuś, A Kusiak - International Journal of Molecular …, 2024 - mdpi.com
Periodontitis is an inflammatory condition affecting the supporting structures of the teeth.
Periodontal conditions may increase the susceptibility of individuals to various systemic …

The impact of the COVID-19 pandemic on dementia risk: potential pathways to cognitive decline

JD Pyne, AM Brickman - Neurodegenerative Diseases, 2021 - karger.com
Abstract Background: Coronavirus disease 2019 (COVID-19), the far-reaching pandemic,
has infected approximately 185 million of the world's population to date. After infection …

LncRNA DLX6-AS1 promotes microglial inflammatory response in Parkinson's disease by regulating the miR-223–3p/NRP1 axis

L Liu, T Zhou, T Li, Z Liang, X Luo - Behavioural Brain Research, 2022 - Elsevier
Parkinson's disease (PD) is a prevailing neurodegenerative disorder. This study discussed
the mechanism of lncRNA distal-less homeobox 6 antisense 1 (DLX6-AS1) on inflammatory …

Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approach

E Alshawaf, MM Hammad, SK Marafie, H Ali… - Microbial …, 2022 - Elsevier
Abstract Neuropilin-1 (NRP1) is a widely expressed cell surface receptor protein
characterized by its pleiotropic function. Recent reports highlighted NRP1 as an additional …

Potent of strategic approaches for tauopathies ranging from single-cell transcriptome to microbiome

SH Kim, S Yang, E Yang, M Kang… - Animal Cells and …, 2023 - Taylor & Francis
Tauopathies as one of the typical neurodegenerative diseases are characterized by
pathologically aggregated tau in neuron and glia, which causes dysfunction, synapse loss …

[HTML][HTML] The VEGFs/VEGFRs system in Alzheimer's and Parkinson's diseases: Pathophysiological roles and therapeutic implications

C Ceci, PM Lacal, ML Barbaccia, NB Mercuri… - Pharmacological …, 2024 - Elsevier
The vascular endothelial growth factors (VEGFs) and their cognate receptors (VEGFRs),
besides their well-known involvement in physiological angiogenesis/lymphangiogenesis …