Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models

Z Cheng, MF White - Antioxidants & redox signaling, 2011 - liebertpub.com
Forkhead box O (FOXO) transcription factors have been implicated in regulating the
metabolism, cellular proliferation, stress resistance, apoptosis, and longevity. Through the …

The role of miR‐378a in metabolism, angiogenesis, and muscle biology

B Krist, U Florczyk… - International journal …, 2015 - Wiley Online Library
MicroRNA‐378a (miR‐378a, previously known as miR‐378) is one of the small noncoding
RNA molecules able to regulate gene expression at posttranscriptional level. Its two mature …

A comparative perspective on lipid storage in animals

K Birsoy, WT Festuccia, M Laplante - Journal of cell science, 2013 - journals.biologists.com
Lipid storage is an evolutionary conserved process that exists in all organisms from simple
prokaryotes to humans. In Metazoa, long-term lipid accumulation is restricted to specialized …

Vascularized adipose tissue engineering: moving towards soft tissue reconstruction

A Peirsman, HT Nguyen, M Van Waeyenberge… - …, 2023 - iopscience.iop.org
Soft tissue defects are a common clinical challenge mostly caused by trauma, congenital
anomalies and oncological surgery. Current soft tissue reconstruction options include …

Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity

JL Morrison, JA Duffield, BS Muhlhausler, S Gentili… - Pediatric …, 2010 - Springer
There is an association between growing slowly before birth, accelerated growth in early
postnatal life and the emergence of insulin resistance, visceral obesity and glucose …

[HTML][HTML] Genome-wide analysis of gene expression during adipogenesis in human adipose-derived stromal cells reveals novel patterns of gene expression during …

MA Ambele, C Dessels, C Durandt, MS Pepper - Stem Cell Research, 2016 - Elsevier
We have undertaken an in-depth transcriptome analysis of adipogenesis in human adipose-
derived stromal cells (ASCs) induced to differentiate into adipocytes in vitro. Gene …

Adipose tissue hypoxia in obesity and its impact on preadipocytes and macrophages: hypoxia hypothesis

A Engin - Obesity and Lipotoxicity, 2017 - Springer
Obese subjects exhibit lower adipose tissue oxygen consumption in accordance with the
lower adipose tissue blood flow. Thus, compared with lean subjects, obese subjects have …

Cellular models for understanding adipogenesis, adipose dysfunction, and obesity

A Armani, C Mammi, V Marzolla… - Journal of cellular …, 2010 - Wiley Online Library
White adipose tissue (WAT) is no longer considered a depot for energy storage in the form of
triglycerides, but is a secretory organ that releases factors, known as adipokines, capable of …

Minireview: PPARγ as the target of obesogens

A Janesick, B Blumberg - The Journal of steroid biochemistry and …, 2011 - Elsevier
The peroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of
adipogenesis and is medically important for its connections to obesity and the treatment of …

Bisphenol F and bisphenol S promote lipid accumulation and adipogenesis in human adipose-derived stem cells

I Reina-Pérez, A Olivas-Martínez, V Mustieles… - Food and Chemical …, 2021 - Elsevier
Bisphenol F (BPF) and bisphenol S (BPS) are increasingly used as substitutes for bisphenol
A (BPA), an endocrine disrupting chemical (EDC) with obesogenic activity. We investigated …