Enhancing the trajectories of cancer health disparities research: improving clinical applications of diversity, equity, inclusion, and accessibility

R Martini, E Gebregzabher, L Newman, MB Davis - Cancer Discovery, 2022 - AACR
In order to accurately detect and prevent racial disparities, self-reported race (SRR) and
ethnicity remain valuable tools; however, inaccurate capture of patient identity and broad …

Human adaptation, demography and cattle domestication: an overview of the complexity of lactase persistence in Africa

MC Campbell, A Ranciaro - Human Molecular Genetics, 2021 - academic.oup.com
Lactase persistence (LP) is a genetically-determined trait that is prevalent in African,
European and Arab populations with a tradition of animal herding and milk consumption. To …

Nutrition, Other Environmental Influences, and Genetics in the Determination of Human Stature

JC Lui, AC Palmer, P Christian - Annual Review of Nutrition, 2024 - annualreviews.org
Linear growth during three distinct stages of life determines attained stature in adulthood:
namely, in utero, early postnatal life, and puberty and the adolescent period. Individual host …

[HTML][HTML] Association between polymorphisms of IL4, IL13, IL10, STAT6 and IFNG genes, cytokines and immunoglobulin E levels with high burden of Schistosoma …

EM Mewamba, H Noyes, AAZ Tiofack… - Infection, Genetics and …, 2023 - Elsevier
Eliminating schistosomiasis as a public health problem by 2030 requires a better
understanding of the disease transmission, especially the asymmetric distribution of worm …

[HTML][HTML] The application of machine learning to predict genetic relatedness using human mtDNA hypervariable region I sequences

P Govender, SG Fashoto, L Maharaj, MA Adeleke… - Plos one, 2022 - journals.plos.org
Human identification of unknown samples following disaster and mass casualty events is
essential, especially to bring closure to family and friends of the deceased. Unfortunately …

Neurogenomics in Africa: perspectives, progress, possibilities and priorities

RO Akinyemi, MO Owolabi, T Oyeniyi… - Journal of the …, 2016 - Elsevier
The understanding of the genetic basis of neurological disorders has grown rapidly in the
last two decades. Despite the genomic heterogeneity within African populations, large-scale …

[HTML][HTML] Developing expertise in bioinformatics for biomedical research in Africa

TK Karikari, E Quansah, WMY Mohamed - Applied & translational genomics, 2015 - Elsevier
Research in bioinformatics has a central role in helping to advance biomedical research.
However, its introduction to Africa has been met with some challenges (such as inadequate …

Human vulnerability and variability in the cold: Establishing individual risks for cold weather injuries

F Haman, SCS Souza, JW Castellani, MP Dupuis… - Temperature, 2022 - Taylor & Francis
Human tolerance to cold environments is extremely limited and responses between
individuals is highly variable. Such physiological and morphological predispositions place …

Perspectives on human variation through the lens of diversity and race

A Chakravarti - Cold Spring Harbor Perspectives in …, 2015 - cshperspectives.cshlp.org
Human populations, however defined, differ in the distribution and frequency of traits they
display and diseases to which individuals are susceptible. These need to be understood …

Genes from the TAS1R and TAS2R Families of Taste Receptors: Looking for Signatures of Their Adaptive Role in Human Evolution

C Valente, L Alvarez, PI Marques… - Genome biology and …, 2018 - academic.oup.com
Taste perception is crucial in monitoring food intake and, hence, is thought to play a
significant role in human evolution. To gain insights into possible adaptive signatures in …