Molecular mechanisms and pathophysiological significance of eryptosis

SA Alghareeb, MA Alfhili, S Fatima - International Journal of Molecular …, 2023 - mdpi.com
Despite lacking the central apoptotic machinery, senescent or damaged RBCs can undergo
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …

Toll-like receptors as pro-thrombotic drivers in viral infections: a narrative review

B Panzer, CW Kopp, C Neumayer, R Koppensteiner… - Cells, 2023 - mdpi.com
Toll-like receptors (TLRs) have a critical role in the pathogenesis and disease course of viral
infections. The induced pro-inflammatory responses result in the disturbance of the …

Effect of silica-based mesoporous nanomaterials on human blood cells

SP Fortis, A Batrinou, HT Georgatzakou… - Chemico-Biological …, 2024 - Elsevier
Different mesoporous nanomaterials (MSNs) are constantly being developed for a range of
therapeutic purposes, but they invariably interact with blood components and may cause …

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo

T Nemkov, D Stephenson, C Erickson… - Blood, 2024 - ashpublications.org
In the field of transfusion medicine, the clinical relevance of the metabolic markers of the red
blood cell (RBC) storage lesion is incompletely understood. Here, we performed …

Exploring unconventional attributes of red blood cells and their potential applications in biomedicine

AT Anastasiadi, VZ Arvaniti, KE Hudson… - Protein & …, 2024 - academic.oup.com
Eukaryotic cells are defined as cells containing distinct nuclei and other membranous
organelles. However, red blood cells (RBCs) lack a nucleus and organelles—perhaps to …

Mechanisms of COVID-19 associated pulmonary thrombosis: a narrative review

CM Niculae, A Hristea, R Moroti - Biomedicines, 2023 - mdpi.com
COVID-19, the infectious disease caused by severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2), is frequently associated with pulmonary thrombotic events, especially in …

SARS-CoV-2 Altered Hemorheological and Hematological Parameters during One-Month Observation Period in Critically Ill COVID-19 Patients

DA Bizjak, L John, L Matits, A Uhl, SVW Schulz… - International journal of …, 2022 - mdpi.com
Hematological and hemorheological parameters are known to be altered in COVID-19;
however, the value of combined monitoring in order to deduce disease severity is only …

COVID-19 impairs oxygen delivery by altering red blood cell hematological, hemorheological, and oxygen transport properties

SC Rogers, M Brummet, Z Safari, Q Wang… - Frontiers in …, 2024 - frontiersin.org
Introduction: Coronavirus disease 2019 (COVID-19) is characterized by impaired oxygen
(O2) homeostasis, including O2 sensing, uptake, transport/delivery, and consumption. Red …

Nutrients, herbal bioactive derivatives and commensal microbiota as tools to lower the risk of SARS-CoV-2 infection

A Romani, D Sergi, E Zauli, R Voltan, G Lodi… - Frontiers in …, 2023 - frontiersin.org
The SARS-CoV-2 outbreak has infected a vast population across the world, causing more
than 664 million cases and 6.7 million deaths by January 2023. Vaccination has been …

Erythrocytes Functionality in SARS-CoV-2 Infection: Potential Link with Alzheimer's Disease

E Kosenko, L Tikhonova, G Alilova… - International Journal of …, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a rapidly spreading acute respiratory infection
caused by SARS-CoV-2. The pathogenesis of the disease remains unclear. Recently …