Purpose To provide clinicians practicing in resource-limited settings with a framework to
improve the diagnosis and treatment of pediatric and adult patients with sepsis. Methods …

Background: Recent clinical trials have shown that adjunctive glucocorticoids is associated
with inhibiting excessive inflammatory response and modulating cytokines release offering …

Critical illnesses are hallmarked by increased systemic cortisol availability, a vital part of the
stress response. Acute stress may trigger a life-threatening adrenal crisis when a disease of …

The multifaceted interaction between coronavirus disease 2019 (COVID-19) and the
endocrine system has been a major area of scientific research over the past two years …

Cirrhotic patients are prone to develop life-threatening complications that require emergency
care and ICU admission. They can present specific decompensations related to cirrhosis …

Sepsis is a major cause of mortality during the neutropenic phase after intensive cytotoxic
therapies for malignancies. Improved management of sepsis during neutropenia may …

Background Hospital-acquired pneumonia is common after traumatic brain injury, and might
be partly a result of traumatic brain injury-induced adrenal insufficiency. We tested the …

Acute pancreatitis in dogs is a potentially reversible condition, but in severe forms it can
cause systemic and local complications. These complications are driven by the cytokine …

Progress has been made in identifying human leukocyte antigen and major
histocompatability complex alleles that predispose to the development of adrenal …

Context: Critical illness, an extreme form of severe physical stress, is characterized by
important endocrine and metabolic changes. Due to critical care medicine, survival from …