Green Tea (Camellia sinensis): A Review of Its Phytochemistry, Pharmacology, and Toxicology

T Zhao, C Li, S Wang, X Song - Molecules, 2022 - mdpi.com
Objectives Green tea (Camellia sinensis) is a kind of unfermented tea that retains the natural
substance in fresh leaves to a great extent. It is regarded as the second most popular drink …

Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?

TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …

[HTML][HTML] Mechanisms of action by sulphur compounds in Allium sativum. A review

AN Jikah, GI Edo - Pharmacological Research-Modern Chinese Medicine, 2023 - Elsevier
Background Allium sativum, the bulbous perennial plant of the Alliaceae family has been
utilized as a very valuable remedy in the management of numerous diseases even from time …

Epigallocatechin gallate (EGCG), a green tea polyphenol, reduces coronavirus replication in a mouse model

R Park, M Jang, YI Park, Y Park, W Jung, J Park, J Park - Viruses, 2021 - mdpi.com
The COVID-19 pandemic has resulted in a huge number of deaths from 2020 to 2021;
however, effective antiviral drugs against SARS-CoV-2 are currently under development …

Role of nuclear factor erythroid 2 (Nrf2) in the recovery of long COVID-19 using natural antioxidants: a systematic review

M Muchtaridi, SR Amirah, JA Harmonis, EHK Ikram - Antioxidants, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is an infectious disease with approximately 517
million confirmed cases, with the average number of cases revealing that patients recover …

[HTML][HTML] Therapeutic potential of green tea catechin,(-)-epigallocatechin-3-O-gallate (EGCG) in SARS-CoV-2 infection: Major interactions with host/virus proteases

B Dinda, S Dinda, M Dinda - Phytomedicine Plus, 2023 - Elsevier
Background The current COVID-19 pandemic from the human pathogenic virus SARS-CoV-
2 has resulted in a major health hazard globally. The morbidity and transmission modality of …

[HTML][HTML] Tea-break with epigallocatechin gallate derivatives–Powerful polyphenols of great potential for medicine

P Bakun, DT Mlynarczyk, T Koczorowski… - European Journal of …, 2023 - Elsevier
Epigallocatechin gallate (EGCG) is a polyphenol present in green tea (Camellia sinensis),
which has revealed anti-cancer effects toward a variety of cancer cells in vitro and protective …

Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

S Zhang, B Mao, S Cui, Q Zhang, J Zhao… - Critical Reviews in …, 2023 - Taylor & Francis
Epigallocatechin gallate (EGCG), a typical flavone-3-ol polyphenol containing eight free
hydroxyl groups, is associated with a variety of bioactivities, such as antioxidant, anti …