The evolution and biology of SARS-CoV-2 variants

A Telenti, EB Hodcroft… - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Our understanding of the still unfolding severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic would have been extremely limited without the study of the …

Targetable elements in SARS-CoV-2 S2 subunit for the design of pan-coronavirus fusion inhibitors and vaccines

L Guo, S Lin, Z Chen, Y Cao, B He, G Lu - Signal Transduction and …, 2023 - nature.com
The ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused devastating impacts …

The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2

JE Pekar, A Magee, E Parker, N Moshiri, K Izhikevich… - Science, 2022 - science.org
Understanding the circumstances that lead to pandemics is important for their prevention.
We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 …

Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential

J Wang, Y Pan, L Yang, W Yang, K Lv, C Luo… - Nature …, 2023 - nature.com
Bats are reservoir hosts for many zoonotic viruses. Despite this, relatively little is known
about the diversity and abundance of viruses within individual bats, and hence the …

[PDF][PDF] Exploring the natural origins of SARS-CoV-2 in the light of recombination

S Lytras, J Hughes, D Martin… - Genome Biology and …, 2022 - academic.oup.com
The lack of an identifiable intermediate host species for the proximal animal ancestor of
SARS-CoV-2, and the large geographical distance between Wuhan and where the closest …

Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant

W Zhang, K Shi, Q Geng, G Ye… - Proceedings of the …, 2022 - National Acad Sciences
The sudden emergence and rapid spread of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) omicron variant has raised questions about its animal …

Host range, transmissibility and antigenicity of a pangolin coronavirus

YJ Hou, S Chiba, SR Leist, RM Meganck… - Nature …, 2023 - nature.com
The pathogenic and cross-species transmission potential of SARS-CoV-2-related
coronaviruses (CoVs) remain poorly characterized. Here we recovered a wild-type pangolin …

Surveillance of SARS-CoV-2 at the Huanan seafood market

WJ Liu, P Liu, W Lei, Z Jia, X He, W Shi, Y Tan, S Zou… - Nature, 2023 - nature.com
Abstract SARS-CoV-2, the causative agent of COVID-19, emerged in December 2019. Its
origins remain uncertain. It has been reported that a number of the early human cases had a …

Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

X Ou, G Xu, P Li, Y Liu, F Zan, P Liu, J Hu, X Lu… - Cell discovery, 2023 - nature.com
The bat coronaviruses (CoV) BANAL-20-52 and BANAL-20-236 are two newly identified
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) closely related …

Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus

J Lee, SK Zepeda, YJ Park, AL Taylor, J Quispe… - Cell Host & Microbe, 2023 - cell.com
Although Rhinolophus bats harbor diverse clade 3 sarbecoviruses, the structural
determinants of receptor tropism along with the antigenicity of their spike (S) glycoproteins …