Many potential immune therapeutic targets are similarly affected in adult-onset
neurodegenerative diseases, such as Alzheimer's (AD) disease, Parkinson's disease (PD) …

Genetic abnormalities play a crucial role in the development of neurodegenerative disorders
(NDDs). Genetic exploration has indeed contributed to unraveling the molecular …

Oxidative stress, which damages cellular components and causes mitochondrial
dysfunction, occurs in a variety of human diseases, including neurological disorders. The …

Exploring shared features in neurodegenerative diseases | Brain | Oxford Academic Skip to Main
Content Advertisement Oxford Academic Journals Books Search Menu Information Account …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by wide
clinical and biological heterogeneity, with a large proportion of ALS patients also exhibiting …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder of
the human motor system, first described in the 19 th Century. The etiology of ALS appears to …

METHODS: We performed single common variant association analysis and rare variant
aggregate analyses in the pooled population (N cases= 2,184, N controls= 2,383) and …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating, immensely complex
neurodegenerative disease by lack of effective treatments. To date, the challenge to …

Neurodegenerative diseases (ND) are heterogeneous disorders of the central nervous
system that share a chronic and selective process of neuronal cell death. A computational …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating, immensely complex
neurodegenerative disease by lack of effective treatments. To date, the challenge to …