[HTML][HTML] Vascular endothelial dysfunction and pharmacological treatment

JB Su - World journal of cardiology, 2015 - ncbi.nlm.nih.gov
The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system

PK Mehta, KK Griendling - American Journal of Physiology …, 2007 - journals.physiology.org
The renin-angiotensin system is a central component of the physiological and pathological
responses of cardiovascular system. Its primary effector hormone, angiotensin II (ANG II), not …

Mechanisms of liver fibrosis

S Tsukada, CJ Parsons, RA Rippe - Clinica chimica acta, 2006 - Elsevier
Liver fibrosis represents a significant health problem worldwide of which no acceptable
therapy exists. The most characteristic feature of liver fibrosis is excess deposition of type I …

[HTML][HTML] Matrix metalloproteinases: the sculptors of chronic cutaneous wounds

VR Krishnaswamy, D Mintz, I Sagi - Biochimica et Biophysica Acta (BBA) …, 2017 - Elsevier
Cutaneous wound healing is a complex mechanism with multiple processes orchestrating
harmoniously for structural and functional restoration of the damaged tissue. Chronic non …

Involvement of tumor necrosis factor-α in angiotensin II–mediated effects on salt appetite, hypertension, and cardiac hypertrophy

S Sriramula, M Haque, DSA Majid, J Francis - Hypertension, 2008 - Am Heart Assoc
Hypertension is considered a low-grade inflammatory condition induced by various
proinflammatory cytokines, including tumor necrosis factor (TNF)-α. Recent studies have …

Angiotensin II and the development of insulin resistance: implications for diabetes

JA Olivares-Reyes, A Arellano-Plancarte… - Molecular and cellular …, 2009 - Elsevier
Angiotensin II (Ang II), the major effector hormone of the renin–angiotensin system (RAS),
has an important role in the regulation of vascular and renal homeostasis. Clinical and …

Structure and activity study of egg protein ovotransferrin derived peptides (IRW and IQW) on endothelial inflammatory response and oxidative stress

K Majumder, S Chakrabarti… - Journal of agricultural …, 2013 - ACS Publications
Egg protein ovotransferrin derived peptides (IRW and IQW) can attenuate tumor necrosis
factor (TNF) induced inflammatory responses and oxidative stress in endothelial cells. The …

HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats

JP Cardinale, S Sriramula, R Pariaut, A Guggilam… - …, 2010 - Am Heart Assoc
Reactive oxygen species and proinflammatory cytokines contribute to cardiovascular
diseases. Inhibition of downstream transcription factors and gene modifiers of these …

Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension

YM Kang, Y Ma, JP Zheng, C Elks… - Cardiovascular …, 2009 - academic.oup.com
Abstract Aims Angiotensin II (ANG II)-induced inflammatory and oxidative stress responses
contribute to the pathogenesis of hypertension. In this study, we determined whether nuclear …

Angiotensin II receptor type 1–An update on structure, expression and pathology

R Eckenstaler, J Sandori, M Gekle… - Biochemical …, 2021 - Elsevier
The AT 1 receptor, a major effector of the renin-angiotensin system, has been extensively
studied in the context of cardiovascular and renal disease. Moreover, angiotensin receptor …