Metallo-β-lactamases (MBLs) are zinc-dependent enzymes capable of hydrolyzing all
bicyclic β-lactam antibiotics, posing a great threat to public health. However, there are …

Background/Objectives: Among various carbapenemases, New Delhi metallo-beta-
lactamases (NDMs) are recognized as the most powerful type capable of hydrolyzing all …

Nanotechnology presents an innovative strategy to combat the spread of antibiotic resistant
bacteria and their resistance genes throughout different ecosystems. To address this …

The upswing of antibiotic resistance is an escalating threat to human health. Resistance
mediated by bacterial metallo-β-lactamases is of particular concern as these enzymes …

The wide spread of antibiotic-resistant “superbugs” containing New Delhi metallo-β-
lactamase-1 (NDM-1) has become a threat to human health. However, clinically valid …

Bacterial resistance to the majority of clinically used β-lactam antibiotics is a global health
threat and, consequently, the driving force for the development of metallo-β-lactamase …

The effectiveness of all antibiotics in the β-lactam group to cure bacterial infections has been
impaired by the introduction of the New Delhi Metallo-β-lactamase (NDM-1) enzyme …

Abstract Metallo-β-lactamases (MBLs) are a class of enzymes that are produced by a variety
of bacterial species and are responsible for conferring resistance to a broad range of β …

Antibiotic resistance is a growing concern in healthcare and medicine. This research was
carried out to analyze whole genome sequences of Klebsiella pneumoniae ST16 with the …

ABSTRACT New Delhi Metallo-β-lactamase (NDM-1) is an enzyme that hydrolyses a wide
range of β-lactam antibiotics, including most carbapenems, leading to antimicrobial …