Drug repurposing approach to fight COVID-19
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …
Natural history of COVID-19 and therapeutic options
P Gautret, M Million, PA Jarrot… - Expert review of …, 2020 - Taylor & Francis
Introduction: COVID-19 presents benign forms in young patients who frequently present with
anosmia. Infants are rarely infected, while severe forms occur in patients over 65 years of …
anosmia. Infants are rarely infected, while severe forms occur in patients over 65 years of …
In silico ADMET and molecular docking study on searching potential inhibitors from limonoids and triterpenoids for COVID-19
Virtual screening of phytochemicals was performed through molecular docking, simulations,
in silico ADMET and drug-likeness prediction to identify the potential hits that can inhibit the …
in silico ADMET and drug-likeness prediction to identify the potential hits that can inhibit the …
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
Drug repurposing (DR): an emerging approach in drug discovery
M Rudrapal, SJ Khairnar… - … , molecular aspects and …, 2020 - books.google.com
Drug repurposing (DR)(also known as drug repositioning) is a process of identifying new
therapeutic use (s) for old/existing/available drugs. It is an effective strategy in discovering or …
therapeutic use (s) for old/existing/available drugs. It is an effective strategy in discovering or …
A deep learning framework for high-throughput mechanism-driven phenotype compound screening and its application to COVID-19 drug repurposing
Phenotype-based compound screening has advantages over target-based drug discovery,
but is unscalable and lacks understanding of mechanism of drug action. A chemical-induced …
but is unscalable and lacks understanding of mechanism of drug action. A chemical-induced …
A review on drug repurposing applicable to COVID-19
S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …
cost and in a shorter time. There are different computational drug-repurposing strategies and …
A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2
Abstract In December 2019, China reported the first cases of the coronavirus disease 2019
(COVID‐19). This disease, caused by the severe acute respiratory syndrome–related …
(COVID‐19). This disease, caused by the severe acute respiratory syndrome–related …
Promising antiviral activities of natural flavonoids against SARS-CoV-2 targets: systematic review
The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …
Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges
V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …