The advances in genetics and biochemistry that have taken place over the last 10 years led
to significant advances in experimental and clinical immunology. In turn, this has led to the …

T cell receptor (TCR)-peptide-major histocompatibility complex (pMHC) interactions play a
vital role in initiating immune responses against pathogens, and the specificity of TCRpMHC …

COVID-19's high virus transmission rates have caused a pandemic that is exacerbated by
the high rates of asymptomatic and presymptomatic infections. These factors suggest that …

Advances in scientific computing have allowed the development of complex models that are
being routinely applied to problems in disease epidemiology, public health and decision …

Ambient Intelligence (AmI) systems require the integration of complex and innovative
solutions. In this sense, agents and multi-agent systems have characteristics such as …

Modern immunology traditionally conceives of the immune system as providing defense
against pathogens. Alfred I. Tauber criticizes this conception of immunity as too narrow …

Viral infectious diseases are a global health concern, as is evident by recent outbreaks of
the middle east respiratory syndrome, Ebola virus disease, and re-emerging zika, dengue …

The mechanisms underlying rapid elimination of herpes simplex virus-2 (HSV-2) in the
human genital tract despite low CD8+ and CD4+ tissue-resident T cell (Trm cell) density are …

Simulations of tissue-specific effects of primary acute viral infections like COVID-19 are
essential for understanding disease outcomes and optimizing therapies. Such simulations …

Viral kinetic (VK) modeling has led to increased understanding of the within host dynamics
of viral infections and the effects of therapy. Here we review recent developments in the …