Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike
many other mature cell types in the adult body, VSMC do not terminally differentiate but …

MicroRNAs (miRNAs) are members of a non-coding RNA family. They act as negative
regulators of protein translation by affecting messenger RNA (mRNA) stability; they …

MicroRNAs (miRNAs) are endogenous, non‐coding RNAs, which have evoked a great deal
of interest due to their importance in many aspects of homeostasis and diseases …

Micro-ribonucleic acids (miRNAs) are in the spotlight as post-transcriptional regulators of
gene expression. More than 1,000 miRNAs are encoded in the human genome. In this …

Heart failure is a global problem with an estimated prevalence of 38 million patients
worldwide, a number that is increasing with the ageing of the population. It is the most …

MicroRNAs (miRNAs) are small, non-coding, RNA molecules approximately 22 nucleotides
in length which act as post-transcriptional regulators of gene expression. Individual miRNAs …

Cardiovascular diseases are one of the most common causes of death in both developing
and developed countries worldwide. Even though there have been improvements in primary …

RNAs not encoding proteins have gained prominence over the last couple of decades as
fundamental regulators of cellular function. Not surprisingly, their dysregulation is …

Background: MicroRNA-22 (miR-22) has recently been reported to play a regulatory role
during vascular smooth muscle cell (VSMC) differentiation from stem cells, but little is known …

Rationale: microRNAs (miRNAs) modulate gene expression by repressing translation of
targeted genes. Previous work has established a role for miRNAs in regulating vascular …