A renal clinician's guide to the gut microbiota

M Snelson, A Biruete, C McFarlane… - Journal of Renal Nutrition, 2020 - Elsevier
It is increasingly recognized that the gut microbiota plays a role in the progression of chronic
diseases and that diet may confer health benefits by altering the gut microbiota composition …

Effects of nonsteroidal anti-inflammatory drugs on the renal excretion of indoxyl sulfate, a nephro-cardiovascular toxin, in rats

CP Yu, DH Sweet, YH Peng, YW Hsieh… - European Journal of …, 2017 - Elsevier
Chronic kidney disease (CKD) is a health problem worldwide. Indoxyl sulfate (IS) is a
nephro-cardiovascular toxin accumulated in CKD patients and cannot be removed through …

A Historical Perspective on Uremia and Uremic Toxins

B Meijers, W Zadora, J Lowenstein - Toxins, 2024 - mdpi.com
Uremia, also known as uremic syndrome, refers to the clinical symptoms in the final stage of
renal failure. The definition of the term has changed over time due to an improved …

The effect and mechanism of Fushen Granule on gut microbiome in the prevention and treatment of chronic renal failure

L Wang, A Xu, J Wang, G Fan, R Liu, L Wei… - Frontiers in Cellular and …, 2024 - frontiersin.org
Background Fushen Granule is an improved granule based on the classic formula Fushen
Formula, which is used for the treatment of peritoneal dialysis-related intestinal dysfunction …

Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium

M Olden, A Teumer, M Bochud, C Pattaro… - American journal of …, 2013 - Elsevier
BACKGROUND: Chronic kidney disease is associated with cardiovascular disease. We
tested for evidence of a shared genetic basis to these traits. STUDY DESIGN: We conducted …

Impact of remote ischemic preconditioning conducted in living kidney donors on renal function in donors and recipients following living donor kidney transplantation: a …

JY Bang, SG Kim, J Oh, SO Kim, YJ Go… - Journal of clinical …, 2019 - mdpi.com
Although remote ischemic preconditioning (RIPC) has been shown to have renoprotective
effects, few studies have assessed the effects of RIPC on renal function in living kidney …

[HTML][HTML] Indoxyl sulfate impairs valsartan-induced neovascularization

KL Kuo, JF Zhao, PH Huang, BC Guo, DC Tarng… - Redox biology, 2020 - Elsevier
Studies revealed that the use of renin-angiotensin-aldosterone system antagonism is not
associated with a statistically significant reduction in the risk of cardiovascular events in …

Postbiotics in oncology: science or science fiction?

A Kudra, K Kaźmierczak-Siedlecka… - Frontiers in …, 2023 - frontiersin.org
The gut microbiome has been increasingly understood to play a critical role in
carcinogenesis and cancer disease progression. The most recent research advancements …

Uremic toxins and atrial fibrillation: mechanisms and therapeutic implications

F Yamagami, K Tajiri, D Yumino, M Ieda - Toxins, 2019 - mdpi.com
Atrial fibrillation (AF) is the most prevalent arrhythmia in the general population. There is a
close association between chronic kidney disease (CKD) and AF. In recent years, attention …

[HTML][HTML] The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease

CJ Wu, CY Chen, TS Lai, PC Wu, CK Chuang, FJ Sun… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Renal anemia is a common complication in patients with advanced chronic kidney disease.
In vitro studies have shown that indoxyl sulfate decreases erythropoietin production …