Mechanical loading, cartilage degradation, and arthritis

HB Sun - Annals of the New York Academy of Sciences, 2010 - Wiley Online Library
Joint tissues are exquisitely sensitive to their mechanical environment, and mechanical
loading may be the most important external factor regulating the development and long‐term …

Stimulation of bone repair with ultrasound: a review of the possible mechanic effects

F Padilla, R Puts, L Vico, K Raum - Ultrasonics, 2014 - Elsevier
In vivo and in vitro studies have demonstrated the positive role that ultrasound can play in
the enhancement of fracture healing or in the reactivation of a failed healing process. We …

Angiogenesis in bone regeneration

KD Hankenson, M Dishowitz, C Gray, M Schenker - Injury, 2011 - Elsevier
Angiogenesis is a key component of bone repair. New blood vessels bring oxygen and
nutrients to the highly metabolically active regenerating callus and serve as a route for …

Remote excitation of neuronal circuits using low-intensity, low-frequency ultrasound

WJ Tyler, Y Tufail, M Finsterwald, ML Tauchmann… - PloS one, 2008 - journals.plos.org
Possessing the ability to noninvasively elicit brain circuit activity yields immense
experimental and therapeutic power. Most currently employed neurostimulation methods …

Physical stimulations for bone and cartilage regeneration

X Huang, R Das, A Patel, T Duc Nguyen - Regenerative engineering and …, 2018 - Springer
A wide range of techniques and methods are actively invented by clinicians and scientists
who are dedicated to the field of musculoskeletal tissue regeneration. Biological, chemical …

The effects of LIPUS on soft-tissue healing: a review of literature

A Khanna, RTC Nelmes, N Gougoulias… - British medical …, 2009 - academic.oup.com
Introduction Ultrasound is widely used for imaging purposes and as an adjunct to
physiotherapy. Low-intensity pulsed ultrasound (LIPUS), having removed the thermal …

Low‐intensity pulsed ultrasound (LIPUS) increases the articular cartilage type II collagen in a rat osteoarthritis model

K Naito, T Watari, T Muta, A Furuhata… - Journal of …, 2010 - Wiley Online Library
In this study, the effect of low‐intensity pulsed ultrasound (LIPUS) on cartilage was
evaluated in a rat osteoarthritis (OA) model using serum biomarkers such as CTX‐II (type II …

[HTML][HTML] Signal transduction in electrically stimulated articular chondrocytes involves translocation of extracellular calcium through voltage-gated channels

J Xu, W Wang, CC Clark, CT Brighton - Osteoarthritis and cartilage, 2009 - Elsevier
OBJECTIVE: To ascertain, using specific inhibitors, the potential role of calcium-related
signal transduction pathways in the mechanism of cartilage matrix protein gene induction …

Low-intensity pulsed ultrasound affects human articular chondrocytes in vitro

CM Korstjens, RHH Van der Rijt, GHR Albers… - Medical & biological …, 2008 - Springer
We investigated whether low-intensity pulsed ultrasound (LIPUS) stimulates chondrocyte
proliferation and matrix production in explants of human articular cartilage obtained from …

Low-intensity pulsed ultrasound accelerated bone-tendon junction healing through regulation of vascular endothelial growth factor expression and cartilage formation

H Lu, L Qin, W Cheung, K Lee, W Wong… - Ultrasound in medicine & …, 2008 - Elsevier
The purpose of this study was to use our established partial patellectomy rabbit model to
study the effects of low-intensity pulsed ultrasound (LIPUS) on patella-patellar tendon (PPT) …