COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy

D Kumar, S Verma, IU Mysorekar - Translational Research, 2023 - Elsevier
As the COVID-19 pandemic continues into its third year, emerging data indicates increased
risks associated with SARS-CoV-2 infection during pregnancy, including pre-eclampsia …

Neurodevelopmental outcomes at 1 year in infants of mothers who tested positive for SARS-CoV-2 during pregnancy

AG Edlow, VM Castro, LL Shook, AJ Kaimal… - JAMA network …, 2022 - jamanetwork.com
Importance Epidemiologic studies suggest maternal immune activation during pregnancy
may be associated with neurodevelopmental effects in offspring. Objective To evaluate …

Impact of perinatal COVID on fetal and neonatal brain and neurodevelopmental outcomes

AC Brum, NE Vain - Seminars in Fetal and Neonatal Medicine, 2023 - Elsevier
After three years of the COVID-19 pandemic, we have learned many aspects of the disease
and the virus: its molecular structure, how it infects human cells, the clinical picture at …

Maternal SARS-CoV-2, placental changes and brain injury in 2 neonates

M Benny, ES Bandstra, AG Saad… - …, 2023 - publications.aap.org
Long-term neurodevelopmental sequelae are a potential concern in neonates following in
utero exposure to severe acute respiratory syndrome coronavirus disease 2 (SARS-CoV-2) …

Sex-specific neurodevelopmental outcomes among offspring of mothers with SARS-CoV-2 infection during pregnancy

AG Edlow, VM Castro, LL Shook, S Haneuse… - JAMA Network …, 2023 - jamanetwork.com
Importance Prior studies using large registries have suggested a modest increase in risk for
neurodevelopmental diagnoses among children of mothers with immune activation during …

Neurodevelopment in infants with antenatal or early neonatal exposure to SARS-CoV-2

SB Mulkey, ME Williams, N Jadeed, A Zhang… - Early human …, 2022 - Elsevier
Background Antenatal and neonatal viral exposure may put the developing brain at risk for
abnormal neurodevelopment. A clinical program at Children's National Hospital provides …

[HTML][HTML] SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders

H Dubey, RK Sharma, S Krishnan… - Frontiers in …, 2022 - frontiersin.org
Pregnant women constitute one of the most vulnerable populations to be affected by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the cause of coronavirus …

[HTML][HTML] Altered purinergic signaling in neurodevelopmental disorders: focus on P2 receptors

M Boccazzi, S Raffaele, T Zanettin, MP Abbracchio… - Biomolecules, 2023 - mdpi.com
With the umbrella term 'neurodevelopmental disorders'(NDDs) we refer to a plethora of
congenital pathological conditions generally connected with cognitive, social behavior, and …

Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

M Massimo, C Barelli, C Moreno, C Collesi… - Brain, 2023 - academic.oup.com
Maternal viral infection and immune response are known to increase the risk of altered
development of the foetal brain. Given the ongoing global pandemic of coronavirus disease …

Prenatal and postnatal neuroimmune interactions in neurodevelopmental disorders

E Kim, JR Huh, GB Choi - Nature Immunology, 2024 - nature.com
The intricate relationship between immune dysregulation and neurodevelopmental
disorders (NDDs) has been observed across the stages of both prenatal and postnatal …