[HTML][HTML] Comorbidities and increased mortality of COVID-19 among the elderly: A systematic review

A Péterfi, Á Mészáros, Z Szarvas, M Pénzes… - Physiology …, 2022 - akjournals.com
Purpose The purpose of current review is to conduct a systematic overview of articles
published between 2019 and 2021 on the relationship of comorbidities and mortality due to …

[HTML][HTML] Local and systemic responses to SARS-CoV-2 infection in children and adults

M Yoshida, KB Worlock, N Huang, RGH Lindeboom… - Nature, 2022 - nature.com
It is not fully understood why COVID-19 is typically milder in children,–. Here, to examine the
differences between children and adults in their response to SARS-CoV-2 infection, we …

[HTML][HTML] Role of senescence in the chronic health consequences of COVID-19

EOW Gerdes, G Vanichkachorn, BP Verdoorn… - Translational …, 2022 - Elsevier
While the full impact of COVID-19 is not yet clear, early studies have indicated that upwards
of 10% of patients experience COVID-19 symptoms longer than 3 weeks, known as Long …

Post-acute sequelae of COVID-19 in older persons: multi-organ complications and mortality

EYF Wan, R Zhang, S Mathur, VKC Yan… - Journal of Travel …, 2023 - academic.oup.com
Introduction Evidence on long-term associations between coronavirus disease 2019 (COVID-
19) and risks of multi-organ complications and mortality in older population is limited. This …

[HTML][HTML] COVID-19 and neurodegenerative diseases: prion-like spread and long-term consequences

N Baazaoui, K Iqbal - Journal of Alzheimer's Disease, 2022 - content.iospress.com
COVID-19 emerged as a global pandemic starting from Wuhan in China and spread at a
lightning speed to the rest of the world. One of the potential long-term outcomes that we …

[HTML][HTML] Comprehensive evaluation of the efficacy and safety of LPV/r drugs in the treatment of SARS and MERS to provide potential treatment options for COVID-19

L Wu, Y Zheng, J Liu, R Luo, D Wu, P Xu, D Wu… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) experienced an outbreak that expanded
worldwide. Lopinavir/ritonavir (LPV/r), which is used effectively for severe acute respiratory …

[HTML][HTML] Melatonin: a ferroptosis inhibitor with potential therapeutic efficacy for the post-COVID-19 trajectory of accelerated brain aging and neurodegeneration

A Yehia, OA Abulseoud - Molecular Neurodegeneration, 2024 - Springer
The unprecedented pandemic of COVID-19 swept millions of lives in a short period, yet its
menace continues among its survivors in the form of post-COVID syndrome. An …

Frailty as a risk factor for post‐acute sequelae of COVID‐19 among US veterans during the Delta and Omicron waves

IS Hammel, DM Tosi, F Tang, H Pott… - Journal of the American …, 2023 - Wiley Online Library
Background Older populations have suffered the highest rates of SARS‐CoV‐2 infection
and associated complications, including Post‐Acute Sequelae of SARS‐CoV‐2 infection …

[HTML][HTML] Agomelatine might be more appropriate for elderly, depressed, type 2 diabetes mellitus patients than paroxetine/fluoxetine

Z Liang, Y Jia, L Zhao, R Zhu, X He, B Tong… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Agomelatine was a novel and melatonergic antidepressant. The present study was
conducted to find out whether age was an important factor for agomelatine in treating …

[HTML][HTML] Multi-omic analysis characterizes molecular susceptibility of receptors to SARS-CoV-2 spike protein

F Wu, C Lin, Y Han, D Zhou, K Chen, M Yang… - Computational and …, 2023 - Elsevier
In the post COVID-19 era, new SARS-CoV-2 variant strains may continue emerging and
long COVID is poised to be another public health challenge. Deciphering the molecular …