Marine sulfated polysaccharides as potential antiviral drug candidates to treat Corona Virus disease (COVID-19)

M Andrew, G Jayaraman - Carbohydrate Research, 2021 - Elsevier
The viral infection caused by SARS-CoV-2 has increased the mortality rate and engaged
several adverse effects on the affected individuals. Currently available antiviral drugs have …

[HTML][HTML] The antiviral activity of bacterial, fungal, and algal polysaccharides as bioactive ingredients: potential uses for enhancing immune systems and preventing …

W Chaisuwan, Y Phimolsiripol, T Chaiyaso… - Frontiers in …, 2021 - frontiersin.org
Viral infections may cause serious human diseases. For instance, the recent appearance of
the novel virus, SARS-CoV-2, causing COVID-19, has spread globally and is a serious …

What are the current anti-COVID-19 drugs? From traditional to smart molecular mechanisms

S Aboul-Fotouh, AN Mahmoud, EM Elnahas, MZ Habib… - Virology journal, 2023 - Springer
Abstract Background Coronavirus disease 19 (COVID-19) is the disease caused by SARS-
CoV-2, a highly infectious member of the coronavirus family, which emerged in December …

The efficacy and safety of remdesivir alone and in combination with other drugs for the treatment of COVID-19: A systematic review and meta-analysis

C Chen, J Fang, S Chen, MJN Rajaofera, X Li… - BMC Infectious …, 2023 - Springer
Background Remdesivir is considered to be a specific drug for treating coronavirus disease
2019. This systematic review aims to evaluate the clinical efficacy and risk of remdesivir …

NSAIDs/nitazoxanide/azithromycin repurposed for COVID-19: potential mitigation of the cytokine storm interleukin-6 amplifier via immunomodulatory effects

MT Kelleni - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
Introduction Mediators of immunity and inflammation are playing a crucial role in COVID-19
pathogenesis and complications as demonstrated by several genetic and clinical studies …

[HTML][HTML] SARS-CoV-2 VOCs, Mutational diversity and clinical outcome: Are they modulating drug efficacy by altered binding strength?

S Saifi, V Ravi, S Sharma, A Swaminathan… - Genomics, 2022 - Elsevier
The global COVID-19 pandemic continues due to emerging Severe Acute Respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC). Here, we performed …

Early treatment of Favipiravir in COVID-19 patients without pneumonia: a multicentre, open-labelled, randomized control study

R Sirijatuphat, W Manosuthi… - Emerging Microbes & …, 2022 - Taylor & Francis
We investigated Favipiravir (FPV) efficacy in mild cases of COVID-19 without pneumonia
and its effects towards viral clearance, clinical condition, and risk of COVID-19 pneumonia …

Beyond vaccines: clinical status of prospective COVID-19 therapeutics

S Kumar, DM Çalışkan, J Janowski, A Faist… - Frontiers in …, 2021 - frontiersin.org
Since November 2019 the SARS-CoV-2 pandemic has caused nearly 200 million infection
and more than 4 million deaths globally (Updated information from the World Health …

Corticosteroids: A boon or bane for COVID-19 patients?

S Sen, B Singh, G Biswas - Steroids, 2022 - Elsevier
Several drugs and antibodies have been repurposed to treat COVID-19. Since the outcome
of the drugs and antibodies clinical studies have been mostly inconclusive or with lesser …

Cost utility analysis of Remdesivir and Dexamethasone treatment for hospitalised COVID-19 patients-a hypothetical study

A Carta, C Conversano - BMC Health Services Research, 2021 - Springer
Abstract Background Sars-Cov-2 is a novel corona virus associated with significant
morbidity and mortality. Remdesivir and Dexamethasone are two treatments that have …