Regenerative medicine is energizing and empowering basic science and has the potential
to dramatically transform health care in the future. Given the remarkable intrinsic …

Background Liver stem cell therapy (SCT) has been suggested as a promising means to
improve liver regeneration in advanced liver disease. However, data from trials are …

Promising preclinical data suggested that bone marrow–derived mesenchymal stem cells
(BM-MSC) can reduce hepatic fibrosis and stimulate liver regeneration. Preclinical studies …

Aim To overcome current limitations of therapy for liver diseases, cell‐based therapies using
mesenchymal stem cells (MSC) have been attempted through basic and clinical …

In this phase I study, we assessed the safety and feasibility of intravenous, autologous bone
marrow (BM) cell therapy, without immunosuppressive preconditioning, in six patients with …

Background As morbidity and mortality from liver disease continues to rise, new strategies
are necessary. Liver transplantation is not only an expensive resource committing the …

Stem cell therapy in chronic liver disease : Current Opinion in Gastroenterology Stem cell
therapy in chronic liver disease : Current Opinion in Gastroenterology Log in or Register …

Hematopoietic stem cells (HSC) represent the prototype stem cell within the body. Since
their discovery, HSC have been the focus of intensive research, and have proven invaluable …

Background aims Macrophages have complex roles in the liver. The aim of this study was to
compare profiles of human monocyte-derived macrophages between controls and cirrhotic …

Liver failure arising from acute and chronic liver disease is an unmet clinical need that
urgently requires novel therapeutic options in addition to orthotopic liver transplantation. Cell …