AIM: To assess the efficacy and safety of bone marrow-derived mesenchymal stem cell (BM-
MSC) in the treatment of decompensated liver cirrhosis. METHODS: The search terms “bone …

End-stage disease due to liver cirrhosis is an important cause of death worldwide. Cirrhosis
results from progressive, extensive fibrosis and impaired hepatocyte regeneration. The only …

Liver transplantation has been accepted as a useful therapeutic approach for patients with
end‐stage liver disease. However, the mismatch between the great demand for liver …

Portal hypertension represents one of the major clinical consequences of chronic liver
disease, having a deep impact on patients' prognosis and survival. Its pathophysiology …

Cirrhosis occurs as a result of various chronic liver injuries, which may be caused by viral
infections, alcohol abuse and the administration of drugs and chemicals. Recently, bone …

The liver is the organ with the highest regenerative capacity in the human body. However,
various insults, including viral infections, alcohol or drug abuse, and metabolic overload …

Background Until now, there is no effective anti-fibrotic therapy available for liver cirrhosis.
Stem cell therapies have been studied for the treatment of hepatic fibrosis. However, the use …

Mesenchymal stem cells (MSCs) are adult stem cells whose self-renewal, multipotency, and
immunosuppressive functions have been investigated for therapeutic applications. MSCs …

Mesenchymal Stem Cells (MSCs) are a population of adherent cells that can differentiate
into mesenchymal lineage populations (cartilage, bone and fat tissue). In addition, they …

Aims: A systematic review and meta-analysis were performed to explore the clinical outcome
of the transplantation of stem cells from various human tissue sources in cirrhotic patients …