Hepatic regenerative potential of mouse bone marrow very small embryonic‐like stem cells

ZH Chen, X Lv, H Dai, C Liu, D Lou… - Journal of cellular …, 2015 - Wiley Online Library
Very small embryonic‐like stem cells (VSELs) are a Sca‐1+ Lin‐CD45‐cell population that
has been isolated from the bone marrow of mice. The similarities and differences between …

Phase 1–2 pilot clinical trial in patients with decompensated liver cirrhosis treated with bone marrow–derived endothelial progenitor cells

D D'Avola, V Fernández-Ruiz, F Carmona-Torre… - Translational …, 2017 - Elsevier
The aim of this nonrandomized, open label, phase 1 clinical trial was to evaluate the safety
and the feasibility of the treatment with autologous bone marrow–derived endothelial …

Bone Marrow–Derived Stromal Cell Therapy in Cirrhosis: Clinical Evidence, Cellular Mechanisms, and Implications for the Treatment of Hepatocellular Carcinoma

JM Vainshtein, R Kabarriti, KJ Mehta… - International Journal of …, 2014 - Elsevier
Current treatment options for hepatocellular carcinoma (HCC) are often limited by the
presence of underlying liver disease. In patients with liver cirrhosis, surgery, chemotherapy …

Assessment of bone marrow-derived Cellular Therapy in progressive Multiple Sclerosis (ACTiMuS): study protocol for a randomised controlled trial

CM Rice, DI Marks, Y Ben-Shlomo, N Evangelou… - Trials, 2015 - Springer
Background We have recently completed an evaluation of the safety and feasibility of
intravenous delivery of autologous bone marrow in patients with progressive multiple …

[HTML][HTML] Outcomes of autologous bone marrow mononuclear cell transplantation in decompensated liver cirrhosis

YQ Bai, YX Yang, YG Yang, SZ Ding… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To determine the long-term efficacy of autologous bone marrow mononuclear cells (BM-
MNCs) transplantation in terms of improving liver function and reducing complications in …

REpeated AutoLogous Infusions of STem cells In Cirrhosis (REALISTIC): a multicentre, phase II, open-label, randomised controlled trial of repeated autologous …

A King, D Barton, HA Beard, N Than, J Moore… - BMJ open, 2015 - bmjopen.bmj.com
Introduction Liver disease mortality and morbidity are rapidly rising and liver transplantation
is limited by organ availability. Small scale human studies have shown that stem cell therapy …

[HTML][HTML] Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress

VCA de Souza, TA Pereira, VW Teixeira… - World Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To evaluate the therapeutic effects of bone marrow-derived CD11b+ CD14+ monocytes
in a murine model of chronic liver damage. METHODS Chronic liver damage was induced in …

[HTML][HTML] Effect of autologous bone marrow stem cell therapy in patients with liver cirrhosis: a meta-analysis

CX Wu, D Wang, Y Cai, AR Luo… - Journal of Clinical and …, 2019 - ncbi.nlm.nih.gov
Abstract Background and Aims: Although autologous bone marrow stem cell (BMSC)
transplantation is an effective treatment for liver cirrhosis, there are few reports describing …

Stem cell therapy for hepatocellular carcinoma and end-stage liver disease

MS Abdellateif, ARN Zekri - Journal of the Egyptian National Cancer …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a major health problem worldwide, especially for
patients who are suffering from end-stage liver disease (ESLD). The ESLD is considered a …

Novelties in the pathophysiology and management of portal hypertension: new treatments on the horizon

SH Kang, MY Kim, SK Baik - Hepatology International, 2018 - Springer
Portal hypertension (PH) is responsible for the most severe complications of cirrhosis and
leading cause of death and liver transplantation. The standard pharmacological treatment …