Liver failure is one of the main causes of death worldwide and is a growing health problem.
Since the discovery of stem cell populations capable of differentiating into specialized cell …

The objective of our study was to assess the effect of human umbilical cord blood (HUCB)
mesenchymal stem cells (MSCs) transplantation on schistosomal hepatic fibrosis in mice …

Chronic liver disease (CLD) is increasing worldwide yet there has been no major advance in
effective therapies for almost five decades. There is mounting evidence that adult …

Background Bone marrow stem/progenitor cells seem to be effective in liver regeneration
after tissue injury. Aim To evaluate the feasibility and safety of the mobilization and …

End-stage liver disease is characterized by massive hepatocyte death resulting in clinical
decompensation and organ failures. Clinical consequences in cirrhosis are the results of the …

The radical treatment currently for decompensated liver cirrhosis is still liver transplantation.
However, liver transplants are not widely performed worldwide and development of genuine …

Alcoholic liver disease affects a great number of people worldwide. With limited therapeutic
options, stem cell therapy offers significant potential for these patients. To date, a limited …

Background aims. Cirrhosis, end-stage liver disease, is caused by different mechanisms of
injury, associated with persistent inflammation. Galectin-3 is an important regulator of …

Diseases of the digestive tract are complex and encompass a broad spectrum of different
pathogeneses (inflammatory, ischemic, neoplastic, and functional deficit). The digestive tract …

Background aims Many rodent experiments and human studies on stem cell therapy have
shown promising therapeutic approaches to liver diseases. We investigated the clinical …