The aim of this review is to present evidence of the impact of ischemic changes in the blood–
brain barrier on the maturation of post-ischemic brain neurodegeneration with features of …

The existence of a selective blood-brain barrier (BBB) and neurovascular coupling are two
unique central nervous system vasculature features that result in an intimate relationship …

Cerebral amyloid angiopathy (CAA) is an important cerebral small vessel disease
associated with brain haemorrhage and cognitive change. The commonest form, sporadic …

Microglia are brain-resident myeloid cells and play a major role in the innate immune
responses of the CNS and the pathogenesis of Alzheimer's disease (AD). However, the …

Extracellular vesicles (EVs) are membrane vesicles that are released extracellularly and
considered to be implicated in the pathogenesis of neurodegenerative diseases including …

Introduction The 5xFAD mouse is a popular model of familial Alzheimer's disease (AD) that
is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements. Despite …

The blood-brain barrier (BBB) is an important barrier separating the central nervous system
from the periphery. The composition includes endothelial cells, pericytes, astrocytes …

This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and
peripheral lipoproteins in the vascular contributions to cognitive impairment and dementia …

Circulating C‐reactive protein (pCRP) concentrations rise dramatically during both acute
(eg, following stroke) or chronic infection and disease (eg, autoimmune conditions such as …

Background: The multi-tasking approach may be promising for cognitive rehabilitation in
cardiac surgery patients due to a significant effect on attentional and executive functions …