Host genetic factors determining COVID-19 susceptibility and severity
TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …
The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …
Elevated interleukin-10 levels in COVID-19: potentiation of pro-inflammatory responses or impaired anti-inflammatory action?
Interleukin (IL)-10 is a pleiotropic cytokine known for its potent anti-inflammatory and
immunosuppressive effects. Originally identified as a product of T helper 2 cells, IL-10 is now …
immunosuppressive effects. Originally identified as a product of T helper 2 cells, IL-10 is now …
IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …
The role of IL-6 and IL-6 blockade in COVID-19
N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …
Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management
Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …
2020 and has affected millions. Several previous studies revealed the impact of the …
COVID19 biomarkers: What did we learn from systematic reviews?
S Semiz - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID19) pandemic continues to represent a substantial
public health concern. It can rapidly progress to severe disease, with poor prognosis and a …
public health concern. It can rapidly progress to severe disease, with poor prognosis and a …
Epigenetic underpinnings of inflammation: Connecting the dots between pulmonary diseases, lung cancer and COVID-19
S Ahmad, S Manzoor, S Siddiqui, N Mariappan… - Seminars in cancer …, 2022 - Elsevier
Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …
JAK inhibitors: Ten years after
Abstract The European Journal of Immunology was launched 50 years ago, coinciding with
the discovery of many cytokines and growth factors and the emergence of an entirely new …
the discovery of many cytokines and growth factors and the emergence of an entirely new …
[HTML][HTML] The potential for Lactoferrin to reduce SARS-CoV-2 induced cytokine storm
M Zimecki, JK Actor, ML Kruzel - International immunopharmacology, 2021 - Elsevier
The COVID-19 pandemic is a serious global health threat caused by severe acute
respiratory syndrome of coronavirus 2 (SARS-CoV-2). Symptoms of COVID-19 are highly …
respiratory syndrome of coronavirus 2 (SARS-CoV-2). Symptoms of COVID-19 are highly …