Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications

YX Xu, SD Pu, X Li, ZW Yu, YT Zhang, XW Tong… - Pharmacological …, 2022 - Elsevier
Exosomes are discoid vesicles with a diameter of 40–160 nm. They are mainly derived from
the multivesicular body formed by the invagination of lysosomal particles in the cell, which …

The impact of diabetes on vascular disease: progress from the perspective of epidemics and treatments

R Liu, L Li, C Shao, H Cai… - Journal of Diabetes …, 2022 - Wiley Online Library
At present, the global incidence of diabetes has increased in countries with large
populations, and the changes in developing regions are particularly worthy of attention. In …

Sanziguben polysaccharides improve diabetic nephropathy in mice by regulating gut microbiota to inhibit the TLR4/NF-κB/NLRP3 signalling pathway

F Wang, C Liu, LZ Ren, YY Li, HM Yang… - Pharmaceutical …, 2023 - Taylor & Francis
Context Sanziguben (SZGB) is an empirical prescription used in traditional Chinese
medicine to treat diabetic nephropathy (DN). As an abundant and primarily effective …

MicroRNA-21: A critical pathogenic factor of diabetic nephropathy

S Liu, W Wu, J Liao, F Tang, G Gao, J Peng… - Frontiers in …, 2022 - frontiersin.org
Diabetic nephropathy (DN), one of the most common and intractable microvascular
complications of diabetes, is the main cause of terminal renal disease globally. MicroRNA …

The role of microRNA in the pathogenesis of diabetic nephropathy

J Szostak, A Gorący, D Durys, P Dec… - International Journal of …, 2023 - mdpi.com
Diabetic nephropathy is one of the most common and severe complications of diabetes
mellitus, affecting one in every five patients suffering from diabetes. Despite extensive …

Gastrodin inhibits high glucose‑induced inflammation, oxidative stress and apoptosis in podocytes by activating the AMPK/Nrf2 signaling pathway

L Huang, M Shao, Y Zhu - … and therapeutic medicine, 2022 - spandidos-publications.com
Diabetic nephropathy (DN) is a serious and common complication of type 1 and 2 diabetes.
Gastrodin has been reported to suppress high glucose (HG)‑induced inflammation and …

[HTML][HTML] An examination of the protective effects and molecular mechanisms of curcumin, a polyphenol curcuminoid in diabetic nephropathy

X Zhu, X Xu, C Du, Y Su, L Yin, X Tan, H Liu… - Biomedicine & …, 2022 - Elsevier
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease and is an
enormous burden on both patients and society. There is an urgent need for effective …

[HTML][HTML] Factores de riesgo de Nefropatía Diabética

A Villena Pacheco - Acta Médica Peruana, 2021 - scielo.org.pe
La nefropatía diabética (ND) es un problema de salud pública cuya prevalencia se
encuentra en continuo incremento, representa una importante carga económica, social y de …

Patterns of toll-like receptor expressions and inflammatory cytokine levels and their implications in the progress of insulin resistance and diabetic nephropathy in type …

RH Aly, AE Ahmed, WG Hozayen, AM Rabea… - Frontiers in …, 2020 - frontiersin.org
Background: Diabetic nephropathy (DNP) is a type 2 diabetes mellitus (T2DM) chronic
complication, which is the largest single cause of end-stage kidney disease. There is an …

Hederagenin inhibits high glucose‐induced fibrosis in human renal cells by suppression of NLRP3 inflammasome activation through reducing cathepsin B expression

G Yang, W Yang, H Jiang, Q Yi… - Chemical Biology & Drug …, 2023 - Wiley Online Library
Diabetic nephropathy is a major complication of diabetes mellitus and is related to
dysfunction of renal cells. Hederagenin is a triterpenoid saponin from some Chinese herbs …