Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins
Y Huang, W Xia, Z Dong, CG Yang - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Epigenetics is brought to RNA, introducing a new dimension to gene
expression regulation. Among numerous RNA modifications, N 6-methyladenosine (m6A) is …
expression regulation. Among numerous RNA modifications, N 6-methyladenosine (m6A) is …
Methylation across the central dogma in health and diseases: new therapeutic strategies
R Liu, E Zhao, H Yu, C Yuan, MN Abbas… - Signal Transduction and …, 2023 - nature.com
The proper transfer of genetic information from DNA to RNA to protein is essential for cell-
fate control, development, and health. Methylation of DNA, RNAs, histones, and non-histone …
fate control, development, and health. Methylation of DNA, RNAs, histones, and non-histone …
A Stapled Peptide Inhibitor Targeting the Binding Interface of N6‐Adenosine‐Methyltransferase Subunits METTL3 and METTL14 for Cancer Therapy
Z Li, Y Feng, H Han, X Jiang, W Chen… - Angewandte Chemie …, 2024 - Wiley Online Library
METTL3, a primary methyltransferase catalyzing the RNA N6‐methyladenosine (m6A)
modification, has been identified as an oncogene in several cancer types and thus …
modification, has been identified as an oncogene in several cancer types and thus …
Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
RK Bedi, D Huang, Y Li, A Caflisch - ACS bio & med chem Au, 2023 - ACS Publications
Methyltransferase-like 3 (METTL3) and METTL14 form a heterodimeric complex that
catalyzes the most abundant internal mRNA modification, N 6-methyladenosine (m6A) …
catalyzes the most abundant internal mRNA modification, N 6-methyladenosine (m6A) …
METTL3 as a novel diagnosis and treatment biomarker and its association with glycolysis, cuproptosis and ceRNA in oesophageal carcinoma
XS Liu, Y Zhang, ZY Liu, Y Gao, LL Yuan… - Journal of Cellular …, 2024 - Wiley Online Library
METTL3 has been shown to be involved in regulating a variety of biological processes.
However, the relationship between METTL3 expression and glycolysis, cuproptosis‐related …
However, the relationship between METTL3 expression and glycolysis, cuproptosis‐related …
[HTML][HTML] METTL3 mediates m6A modification of hsa_circ_0072380 to regulate the progression of gestational diabetes mellitus
S Zhang, S Cai, L Ye, L Shen, C Zhu, J Huang, Z Wang… - Gene, 2024 - Elsevier
Background m6A modification plays a vital role in gestational diabetes mellitus (GDM)
progression. However, the role of METTL3 and differential m6A-modified circRNAs in GDM …
progression. However, the role of METTL3 and differential m6A-modified circRNAs in GDM …
METTL3 as a novel diagnosis and treatment biomarker and its association with glycolysis, cuproptosis and ceRNA in oesophageal carcinoma
L Xu-Sheng, Y Zhang, L Zi-Yue, Y Gao… - Journal of Cellular …, 2024 - search.proquest.com
METTL3 has been shown to be involved in regulating a variety of biological processes.
However, the relationship between METTL3 expression and glycolysis, cuproptosis-related …
However, the relationship between METTL3 expression and glycolysis, cuproptosis-related …
A Stapled Peptide Inhibitor of METTL3-METTL14 for Cancer Therapy
Z Li, Y Feng, H Han, X Jiang, W Chen, X Ma, Y Mei… - bioRxiv, 2023 - biorxiv.org
METTL3, a primary methyltransferase catalyzing RNA N6-methyladenosine (m6A)
modification, has been identified as an oncogene in several cancer types and thus …
modification, has been identified as an oncogene in several cancer types and thus …
[PDF][PDF] The indispensability of methyltransferase-like 3 in the immune system: From maintaining homeostasis to driving function.
X Su - directivepublications.org
ABSTRACT Methyltransferase-like 3 (METTL3), recognized as the primary N6-
methyladenosine methyltransferase, influences cellular functions such as proliferation …
methyladenosine methyltransferase, influences cellular functions such as proliferation …