Although vaccination against SARS-CoV-2 infection has been initiated, effective therapies for severe COVID-19 disease are still needed. A promising therapeutic strategy is using FDA …
B Mhlekude, D Postmus, J Weiner 3rd, S Stenzel… - bioRxiv, 2022 - biorxiv.org
Inhibitors of bromodomain and extra-terminal proteins (iBETs), including JQ-1, have been suggested as potential therapeutics against SARS-CoV-2 infection. However, molecular …
R Hazari, P Pal Chaudhuri - International Journal of Parallel …, 2022 - Taylor & Francis
The reason of significantly higher transmissibility of SARS Covid (2019 CoV-2) compared with SARS Covid (2003 CoV) and MERS Covid (2012 MERS) can be attributed to mutations …
The less virulent human (h) coronaviruses (CoVs) 229E, NL63, OC43, and HKU1 cause mild, self-limiting respiratory tract infections, while the more virulent SARS-CoV-1, MERS …
S Bihani, S Aggarwal… - Multi-Pronged Omics …, 2022 - api.taylorfrancis.com
Pathogenesis by an infecting organism is a victory of pathogen infectivity on the targeted host. It is often precipitated by the insufficiency of the host immune system to tackle the …
Since the emergence of the SARS-CoV-2 induced COVID-19 pandemic, millions of patients have been diagnosed for the disease and many of them have died worldwide. SARS-CoV-2 …
The less virulent human (h) coronaviruses (CoVs) 229E, NL63, OC43, and HKU1 cause mild, self-limiting respiratory tract infections, while the more virulent SARS-CoV-1, MERS …
E Lawani-Luwaji, T Alade, BU John - 2023 - abjournals.org
Viruses undergo mutations over time, and sometimes these changes do not have any significant impact on the virus's pro Page 1 African Journal of Biology and Medical Research ISSN …
Viroporins are a class of viral membrane proteins that play diverse roles in the viral infection cycle. Viroporins are known to play roles in ion transport, inducing membrane curvature, as …