Lung fibrosis after COVID-19: treatment prospects

E Bazdyrev, P Rusina, M Panova, F Novikov… - Pharmaceuticals, 2021 - mdpi.com
At the end of 2019, a highly contagious infection began its ominous conquest of the world. It
was soon discovered that the disease was caused by a novel coronavirus designated as …

Idiopathic pulmonary fibrosis: pathogenesis and management

G Sgalla, B Iovene, M Calvello, M Ori, F Varone… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease
characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma …

The therapy of idiopathic pulmonary fibrosis: what is next?

V Somogyi, N Chaudhuri, SE Torrisi… - European …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease, characterised by progressive scarring of the lung and associated with a high …

A Phase IIb Randomized Clinical Study of an Anti-αvβ6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis

G Raghu, M Mouded, DC Chambers… - American journal of …, 2022 - atsjournals.org
Rationale: Treatment options for idiopathic pulmonary fibrosis (IPF) are limited. Objectives:
To evaluate the efficacy and safety of BG00011, an anti-αvβ6 IgG1 monoclonal antibody, in …

Pharmacological management of progressive-fibrosing interstitial lung diseases: a review of the current evidence

L Richeldi, F Varone, M Bergna… - European …, 2018 - Eur Respiratory Soc
A proportion of patients with interstitial lung diseases (ILDs) are at risk of developing a
progressive-fibrosing phenotype, which is associated with a deterioration in lung function …

Tele-rehabilitation program in idiopathic pulmonary fibrosis—a single-center randomized trial

J Cerdan-de-Las-Heras, F Balbino, A Løkke… - International Journal of …, 2021 - mdpi.com
We investigated the usefulness and effectiveness of tele-rehabilitation on exercise capacity
in patients with idiopathic pulmonary fibrosis (IPF). A randomized study was carried out …

Idiopathic pulmonary fibrosis and post-COVID-19 lung fibrosis: links and risks

F Patrucco, P Solidoro, F Gavelli, D Apostolo, M Bellan - Microorganisms, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is considered the paradigmatic example of chronic
progressive fibrosing disease; IPF does not result from a primary immunopathogenic …

[HTML][HTML] Exosomes in chronic respiratory diseases

B Purghè, M Manfredi, B Ragnoli, G Baldanzi… - Biomedicine & …, 2021 - Elsevier
Exosomes are nano-sized vesicles released by almost all cell types, with a central role as
mediators of intercellular communication. In addition to physiological conditions, these …

SAR156597 in idiopathic pulmonary fibrosis: a phase 2 placebo-controlled study (DRI11772)

G Raghu, L Richeldi, B Crestani… - European …, 2018 - Eur Respiratory Soc
A phase 2b trial (NCT02345070) was conducted to evaluate the efficacy and safety of two
dose levels/regimens of SAR156597 (a bispecific IgG4 antibody that binds and neutralises …

[PDF][PDF] Overview of idiopathic pulmonary fibrosis, evidence-based guidelines, and recent developments in the treatment landscape

MK Glassberg - Am J Manag Care, 2019 - ajmc.s3.amazonaws.com
Along with increasing age and male sex, potential risk factors for IPF include cigarette
smoking, environmental exposures, microbial pathogens, and genetic factors. 1 Anyone with …