Spontaneous Decoration of Ultrasmall Pt Nanoparticles on Size‐Separated MoS2 Nanosheets

K Lobo, VK Gangaiah, C Alex, NS John… - … A European Journal, 2023 - Wiley Online Library
Liquid exfoliation can be considered as a viable approach for the scalable production of 2D
materials due to its various benefits, although the polydispersity in the obtained nanosheet …

[PDF][PDF] Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes

KS Burch, K Hou, Y Ding, Y Wang, S Gazal… - The American Journal of …, 2022 - cell.com
Recent works have shown that SNP heritability—which is dominated by low-effect common
variants—may not be the most relevant quantity for localizing high-effect/critical disease …

XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias

M Cai, Z Wang, J Xiao, X Hu, G Chen… - Nature Communications, 2023 - nature.com
Fine-mapping prioritizes risk variants identified by genome-wide association studies
(GWASs), serving as a critical step to uncover biological mechanisms underlying complex …

Cross-ancestry genetic architecture and prediction for cholesterol traits

MM Momin, X Zhou, E Hyppönen, B Benyamin, SH Lee - Human Genetics, 2024 - Springer
While cholesterol is essential, a high level of cholesterol is associated with the risk of
cardiovascular diseases. Genome-wide association studies (GWASs) have proven …

Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis of the United Kingdom Biobank and Taiwan Biobank

E Hassanin, KH Lee, TC Hsieh, R Aldisi, YL Lee… - Frontiers in …, 2023 - frontiersin.org
Polygenic risk score (PRS) predictions often show bias toward the population of available
genome-wide association studies (GWASs), which is typically of European ancestry. This …

[PDF][PDF] Occupational stress and sleep among teachers: What is the effective-ness of a programme to reduce occupational stress using mindfulness

S Inácio, L Pitacho, A Moreira… - Scholarly Journal of …, 2023 - researchgate.net
In Portugal, teachers are subjected to numerous sources of pressure, which leads us to be a
country with very high levels of occupational stress in this professional group. Occupational …

[PDF][PDF] Multivariate extension of penalized regression on summary statistics to construct polygenic risk scores for correlated traits

M Bahda, J Ricard, SL Girard, M Maziade… - Human Genetics and …, 2023 - cell.com
Genetic correlations between human traits and disorders such as schizophrenia (SZ) and
bipolar disorder (BD) diagnoses are well established. Improved prediction of individual traits …

Populations, traits, and their spatial structure in humans

M Sohail, A Izarraras-Gomez… - Genome Biology and …, 2021 - academic.oup.com
The spatial distribution of genetic variants is jointly determined by geography, past
demographic processes, natural selection, and its interplay with environmental variation. A …

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults

A Pozarickij, W Gan, K Lin, R Clarke, Z Fairhurst-Hunter… - medRxiv, 2023 - medrxiv.org
Elevated blood pressure (BP) is major risk factor for cardiovascular diseases (CVD).
Genome-wide association studies (GWAS) conducted predominantly in populations of …

[HTML][HTML] Ancestry-specific regulatory and disease architectures are likely due to cell-type-specific gene-by-environment interactions

J Wang, S Gazal - medRxiv, 2023 - ncbi.nlm.nih.gov
Multi-ancestry genome-wide association studies (GWAS) have highlighted the existence of
variants with ancestry-specific effect sizes. Understanding where and why these ancestry …