Polygenic risk score (PRS) has demonstrated its great utility in biomedical research through
identifying high-risk individuals for different diseases from their genotypes. However, the …

Multi-ancestry statistical fine-mapping of cis-molecular quantitative trait loci (cis-molQTL)
aims to improve the precision of distinguishing causal cis-molQTLs from tagging variants …

The development of photoactive materials based on single-atom catalysts is essential to
improve the performance of photoelectrochemical (PEC) biosensors. Herein, we have …

Precision medicine aims to create biomedical solutions tailored to specific factors that affect
disease risk and treatment responses within the population. The success of the genomics …

Atmospheric water harvesting is urgently needed given increasing global water scarcity.
Current sorbent-based devices that cycle between water capture and release have low …

The solar evaporation system has become a research hotspot in the field of photothermal
conversion technology in recent years because of its high photothermal conversion …

Apart from ancestry, personal or environmental covariates may contribute to differences in
polygenic score (PGS) performance. We analyzed effects of covariate stratification and …

Polygenic risk scores (PRS) have led to enthusiasm for precision medicine. However, it is
well documented that PRS do not generalize across groups differing in ancestry or sample …

Recent advances in genome-wide association and sequencing studies have shown that the
genetic architecture of complex traits and diseases involves a combination of rare and …

Modulating the local coordination environment of catalysts is of overriding importance to
control reactivity, but systematic investigation of catalytic active sites with different …