Potent cross-reactive antibodies following Omicron breakthrough in vaccinees
Highly transmissible Omicron variants of SARS-CoV-2 currently dominate globally. Here, we
compare neutralization of Omicron BA. 1, BA. 1.1, and BA. 2. BA. 2 RBD has slightly higher …
compare neutralization of Omicron BA. 1, BA. 1.1, and BA. 2. BA. 2 RBD has slightly higher …
A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses
The threat of spillovers of coronaviruses associated with the severe acute respiratory
syndrome (SARS) from animals to humans necessitates vaccines that offer broader …
syndrome (SARS) from animals to humans necessitates vaccines that offer broader …
The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants
Summary Alpha-B. 1.1. 7, Beta-B. 1.351, Gamma-P. 1, and Delta-B. 1.617. 2 variants of
SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the …
SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the …
Pseudoviruses, a safer toolbox for vaccine development against enveloped viruses
Introduction Pseudoviruses are recombinant, replication-incompetent, viral particles
designed to mimic the surface characteristics of native enveloped viruses. They are a safer …
designed to mimic the surface characteristics of native enveloped viruses. They are a safer …
Quantifying neutralising antibody responses against SARS-CoV-2 in dried blood spots (DBS) and paired sera
KJ Roper, J Thomas, W Albalawi, E Maddocks… - Scientific Reports, 2023 - nature.com
The ongoing SARS-CoV-2 pandemic was initially managed by non-pharmaceutical
interventions such as diagnostic testing, isolation of positive cases, physical distancing and …
interventions such as diagnostic testing, isolation of positive cases, physical distancing and …
The ecology of viruses in urban rodents with a focus on SARS-CoV-2
Wild animals are naturally infected with a range of viruses, some of which may be zoonotic.
During the human COVID pandemic there was also the possibility of rodents acquiring …
During the human COVID pandemic there was also the possibility of rodents acquiring …
The pilot study of immunogenicity and adverse events of a COVID-19 vaccine regimen: priming with inactivated whole SARS-CoV-2 vaccine (CoronaVac) and …
S Mahasirimongkol, A Khunphon, O Kwangsukstid… - Vaccines, 2022 - mdpi.com
In response to the SARS-CoV-2 Delta variant, which partially escaped the vaccine-induced
immunity provided by two doses of vaccination with CoronaVac (Sinovac), the National …
immunity provided by two doses of vaccination with CoronaVac (Sinovac), the National …
Complement activation-independent attenuation of SARS-CoV-2 infection by C1q and C4b-binding protein
The complement system is a key component of the innate immune response to viruses and
proinflammatory events. Exaggerated complement activation has been attributed to the …
proinflammatory events. Exaggerated complement activation has been attributed to the …
Assessment of safety and intranasal neutralizing antibodies of HPMC-based human anti-SARS-CoV-2 IgG1 nasal spray in healthy volunteers
T Imsuwansri, T Jongthitinon, N Pojdoung… - Scientific Reports, 2023 - nature.com
An HPMC-based nasal spray solution containing human IgG1 antibodies against SARS-
CoV-2 (nasal antibody spray or NAS) was developed to strengthen COVID-19 management …
CoV-2 (nasal antibody spray or NAS) was developed to strengthen COVID-19 management …
Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants
GW Carnell, M Billmeier, S Vishwanath… - Frontiers in …, 2023 - frontiersin.org
The accelerated development of the first generation COVID-19 vaccines has saved millions
of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The …
of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The …