RNA modifications: importance in immune cell biology and related diseases

L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

The role of viral infections in the onset of autoimmune diseases

B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Risk of autoimmune diseases in patients with COVID-19: a retrospective cohort study

R Chang, TYT Chen, SI Wang, YM Hung… - …, 2023 - thelancet.com
Background There are a growing number of case reports of various autoimmune diseases
occurring after COVID-19, yet there is no large-scale population-based evidence to support …

Molecular mechanisms of neutrophil extracellular trap (NETs) degradation

U Demkow - International Journal of Molecular Sciences, 2023 - mdpi.com
Although many studies have been exploring the mechanisms driving NETs formation, much
less attention has been paid to the degradation and elimination of these structures. The …

Good's syndrome: time to move on from reviewing the past

A Kabir, R Alizadehfar, CM Tsoukas - Frontiers in Immunology, 2022 - frontiersin.org
For seven decades, the pathophysiology of Good's syndrome (GS) has remained a mystery,
with few attempts to solve it. Initially described as an association between …

The link between rheumatic disorders and inborn errors of immunity

G Sogkas, T Witte - EBioMedicine, 2023 - thelancet.com
Inborn errors of immunity (IEIs) are immunological disorders characterized by variable
susceptibility to infections, immune dysregulation and/or malignancies, as a consequence of …

Common variable immunodeficiency-associated cancers: the role of clinical phenotypes, immunological and genetic factors

L Bruns, V Panagiota, S von Hardenberg… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to investigate the prevalence of cancer and associating
clinical, immunological, and genetic factors in a German cohort of patients with common …

[HTML][HTML] Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry

M Jamee, G Azizi, S Baris, E Karakoc-Aydiner… - Clinical …, 2022 - Elsevier
Monogenic immune dysregulation diseases (MIDD) are caused by defective
immunotolerance. This study was designed to increase knowledge on the prevalence and …

Dominant-negative heterozygous mutations in AIRE confer diverse autoimmune phenotypes

BE Oftedal, K Assing, S Baris, SL Safgren, IS Johansen… - Iscience, 2023 - cell.com
Autoimmune polyendocrine syndrome type 1 (APS-1) is an autosomal recessive disease
characterized by severe and childhood onset organ-specific autoimmunity caused by …

[HTML][HTML] Role of the Hippo pathway in autoimmune diseases

H Kong, JJ Han, D Gorbachev, XA Zhang - Experimental Gerontology, 2024 - Elsevier
The immune system is an important defense against diseases, and it is essential to maintain
the homeostasis of the body's internal environment. Under normal physiological conditions …