The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat.

AC Issekutz, TB Issekutz - Immunology, 1992 - ncbi.nlm.nih.gov
Recently the critical requirement for the CD18 family of adhesion molecules on leucocytes
for their adhesion and migration to inflammatory reactions has been recognized in humans …

Treatment with anti‐CR3 antibodies ED7 and ED8 suppresses experimental allergic encephalomyelitis in Lewis rats

I Huitinga, JGMC Damoiseaux… - European journal of …, 1993 - Wiley Online Library
Experimental allergic encephalomyelitis (E AE) is an inflammatory disease of the central
nervous system (CNS). Among the leukocytes which infiltrate the CNS during EAE …

Role of leukocyte adhesion molecules in lung and dermal vascular injury after thermal trauma of skin.

MS Mulligan, GO Till, CW Smith… - The American journal …, 1994 - ncbi.nlm.nih.gov
Acute second degree thermal injury of rat skin involving 25 to 30% total body surface of
anesthetized rats results at 4 hours in evidence of vascular injury both locally (in skin) and …

Intraepithelial airway dendritic cells: a distinct subset of pulmonary dendritic cells obtained by microdissection.

JL Gong, KM McCarthy, J Telford, T Tamatani… - The Journal of …, 1992 - rupress.org
Dendritic cells (DC), in general, and pulmonary DC, in particular, are a heterogeneous
population of cells, their phenotype and function being dependent on their anatomic …

The subarachnoid space as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis

T Shin, T Kojima, N Tanuma, Y Ishihara… - Journal of …, 1995 - Elsevier
To characterize the phenotype of inflammatory cells in the central nervous system (CNS) in
experimental autoimmune encephalomyelitis (EAE), Lewis rats were immunized with guinea …

Estrogens inhibit angiotensin II–induced leukocyte–endothelial cell interactions in vivo via rapid endothelial nitric oxide synthase and cyclooxygenase activation

A Álvarez, C Hermenegildo, AC Issekutz… - Circulation …, 2002 - Am Heart Assoc
Angiotensin II (Ang II) may be a key molecule in the development of atherosclerosis.
Because the incidence of coronary atherosclerosis in premenopausal women is lower than …

Hepatocyte survival depends on β1‐integrin‐mediated attachment of hepatocytes to hepatic extracellular matrix

GGM Pinkse, MP Voorhoeve, M Noteborn… - Liver …, 2004 - Wiley Online Library
Background: A major drawback of allogeneic hepatocyte transplantation is the lack of
sustained survival of the transplanted cells in the recipient liver parenchyma. The purpose of …

Molecular determinants of oxidized low-density lipoprotein–induced leukocyte adhesion and microvascular dysfunction

L Liao, RM Starzyk, DN Granger - Arteriosclerosis, thrombosis, and …, 1997 - Am Heart Assoc
Oxidized low-density lipoproteins (oxLDL) have been implicated in the leukocyte recruitment
and microvascular dysfunction associated with atherosclerosis. The objectives of this study …

Acute Pancreatitis: The Pathophysiological Role of Cytokines and Integrins: New Trends for Treatment?

MO Osman, SL Jensen - Digestive surgery, 1999 - karger.com
As Moynihan [1] wrote in 1925,'Acute pancreatitis (AP) is the most terrible of all the
calamities that occur in connection with the abdominal viscera. The suddenness of its onset …

Interleukin-1 receptor antagonist ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis.

WW Tang, L Feng, JL Vannice… - The Journal of clinical …, 1994 - Am Soc Clin Investig
The contribution of IL-1 to leukocyte infiltration in anti-glomerular basement membrane
(GBM) antibody (Ab) glomerulonephritis (GN) was examined by the administration of a …