Efficacy of intraportal injection of anti-ICAM-1 monoclonal antibody against liver cell injury following warm ischemia in the rat

H Nakano, M Kuzume, K Namatame… - The American journal of …, 1995 - Elsevier
Background: Increased expression of intercellular adhesion molecule-1 (ICAM-1) and
lymphocyte-function-associated antigen-1 (LFA-1) has been reported to play a major role in …

Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine.

I Kurose, C Pothoulakis, JT LaMont… - The Journal of …, 1994 - Am Soc Clin Investig
Clostridium difficile toxin A (Tx-A) mediates secretion and inflammation in experimental
enterocolitis. Intravital video microscopy was used to define the mechanisms that underlie …

Role of neutrophil-mediated inflammation in aspirin-induced gastric mucosal injury

N Yoshida, T Yoshikawa, Y Nakamura, M Arai… - Digestive diseases and …, 1995 - Springer
The objectives of this study were to determine the roles of neutrophil-endothelial cell
interactions and oxygen-derived free radicals in the pathogenesis of aspirin-induced gastric …

[PDF][PDF] Role of adhesion molecules in the development of massive hepatic necrosis in rats

S Mochida, A Ohno, M Arai, T Tamatani… - …, 1996 - Wiley Online Library
Massive hepatic necrosis develops after endotoxin administration in rats pretreated with
heat‐killed Propionibacterium acnes as a result of microcirculatory disturbance caused by …

Defective costimulatory function is a striking feature of antigen‐presenting cells in an HLA–B27–transgenic rat model of spondylarthropathy

C Hacquard‐Bouder, G Falgarone… - Arthritis & …, 2004 - Wiley Online Library
Objective A disease resembling the human spondylarthropathies develops in HLA–B27–
transgenic rats. This disease in rats is mediated by CD4+ T cells, but antigen‐presenting …

Macrophage Heterogeneity Established by Immunocytochemistiry

CD Dijrstra, JGMC Damoiseaux - Progress in histochemistry and …, 1993 - Elsevier
Macrophage heterogeneity and microenvironment Phagocytosis by scavenger
macrophages. Complementreceptors.... Immunoglobulinreceptors........ Lysosomal …

Characterization of rat LECAM‐1 (L‐selectin) by the use of monoclonal antibodies and evidence for the presence of soluble LECAM‐1 in rat sera

T Tamatani, F Kitamura, K Kuida… - European journal of …, 1993 - Wiley Online Library
We have characterized the rat LECAM‐1 (L‐selectin) by the use of newly generated hamster
anti‐rat LECAM‐1 monoclonal antibodies (mAb)(HRL1, HRL2, HRL3, HRL4), with respect to …

Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair

AD Gaudet, DR Sweet, NK Polinski, Z Guan… - Molecular and Cellular …, 2015 - Elsevier
Abstract Galectin (Gal)-1 is a small carbohydrate-binding protein and immune modulatory
cytokine that is synthesized locally at the site of peripheral nerve injury. In this environment …

Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties

K Chiba, K Adachi - US Patent 6,004,565, 1999 - Google Patents
Lenahan PLLC 57 ABSTRACT The methods and compositions of the invention and the
compounds used in the invention involve a novel immuno Suppression mechanism …

Lymphocyte migration into the CNS modelled in vitro: roles of LFA-1, ICAM-1 and VLA-4.

D Male, J Rahman, G Pryce, T Tamatani… - Immunology, 1994 - ncbi.nlm.nih.gov
We examined the changes in intercellular adhesion molecule-1 (ICAM-1) expression on
brain endothelium in response to tumour necrosis factor-alpha (TNF-alpha) and interferon …