Aging exhibits several hallmarks in common with cancer, such as cellular senescence,
dysbiosis, inflammation, genomic instability, and epigenetic changes. In recent decades …

Background: Aging involves intricate epigenetic changes, with histone modifications playing
a pivotal role in dynamically regulating gene expression. Our research comprehensively …

Health problems associated with aging are a major public health concern for the future.
Aging is a complex process with wide intervariability among individuals. Therefore, there is a …

Heterochronic parabiosis (HPB) is known for its functional rejuvenation effects across
several mouse tissues. However, its impact on the biological age of organisms and their …

DNA methylation is the most stable epigenetic modification. In mammals, it usually occurs at
the cytosine of CpG dinucleotides. DNA methylation is essential for many physiological and …

Comparative studies of aging are a promising approach to identifying general properties of
and processes leading to aging. While to date, many comparative studies of aging in …

The exponential scientific and technological progress during the past 30 years has favored
the comprehensive characterization of aging processes with their multivariate nature …

DeepMAge is a deep-learning DNA methylation aging clock that measures the organismal
pace of aging with the information from human epigenetic profiles. In blood samples …

Awareness of work-related stress or mental health has been increasing in global tourism,
but there has often been a dilemma to deal with it properly. In this paper, we adopted the …

DNA methylation clocks estimate biological age based on DNA methylation profiles. This
study developed a mathematical model to describe DNA methylation aging and the …