Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

Mitochondria are major sources of reactive oxygen species (ROS) within the cell and are
especially vulnerable to oxidative stress. Oxidative damage to mitochondria results in …

Owing to the dominant functions of mitochondria in multiple cellular metabolisms and distinct
types of regulated cell death, maintaining a functional mitochondrial network is fundamental …

T cells undergo metabolic reprogramming and multiple biological processes to satisfy their
energetic and biosynthetic demands throughout their lifespan. Several of these metabolic …

Mitochondria are a main source of cellular energy. Oxidative phosphorylation (OXPHOS) is
the major process of aerobic respiration. Enzyme complexes of the electron transport chain …

Heavy metal cadmium (Cd), a classical environmental pollutant, causes placental apoptosis
and fetal growth restriction (FGR), whereby the mechanism remains unclear. Here, our …

Aging, in a large measure, has long been defined as the resultant of oxidative stress acting
on the cells. The cellular machinery eventually malfunctions at the basic level by the …

Mitochondria are key regulators of cell fate through controlling ATP generation and
releasing pro-apoptotic factors. Cardiac ischemia/reperfusion (I/R) injury to the coronary …

In the modern era, physical and mental stress lead to anxiety at an alarming rate. Therefore,
searching for new lead compounds that deal with anxiety has a practical demand. Our study …

The brain requires a large amount of energy. Its function can be altered when energy
demand exceeds supply or during metabolic disturbances such as diabetes mellitus …