Background: Numerous risk factors for dementia are well established, though the causal
nature of these associations remains unclear. Objective: To systematically review Mendelian …

Sex steroid receptors have received much interest as potential mediators of human
behaviors and mental disorders. Candidate gene association studies have identified about …

A fair number of epidemiological studies suggest that age at menarche (AAM) is associated
with depression, but the reported effect sizes are small, and there is evidence of residual …

Context The timing of puberty, physical features of pubertal development, and hormones are
closely intertwined but may also individually contribute to the risk for depression and …

To clarify the causal role of age at menarche in depressive symptoms we conducted a
Mendelian randomization study using a large Southern Chinese cohort (n= 12,233). A …