[HTML][HTML] Next-generation TB vaccines: progress, challenges, and prospects

L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …

[HTML][HTML] The quest for nanoparticle-powered vaccines in cancer immunotherapy

Z Sun, H Zhao, L Ma, Y Shi, M Ji, X Sun, D Ma… - Journal of …, 2024 - Springer
Despite recent advancements in cancer treatment, this disease still poses a serious threat to
public health. Vaccines play an important role in preventing illness by preparing the body's …

Stereoselective Synthesis of Sialyl Lewisa Antigen and the Effective Anticancer Activity of Its Bacteriophage Qβ Conjugate as an Anticancer Vaccine

Z Rashidijahanabad, S Ramadan… - Angewandte Chemie …, 2023 - Wiley Online Library
Sialyl Lewisa (sLea), also known as cancer antigen 19‐9 (CA19‐9), is a tumor‐associated
carbohydrate antigen. The overexpression of sLea on the surface of a variety of cancer cells …

Development of a Tag/Catcher-mediated capsid virus-like particle vaccine presenting the conserved Neisseria gonorrhoeae SliC antigen that blocks human lysozyme

FG Martinez, RA Zielke, CE Fougeroux, L Li… - Infection and …, 2023 - Am Soc Microbiol
Virus-like particles (VLPs) are promising nanotools for the development of subunit vaccines
due to high immunogenicity and safety. Herein, we explored the versatile and effective …

Enhancing Protective Antibodies against Opioids through Antigen Display on Virus-like Particles

F Shafieichaharberoud, S Lang, C Whalen… - Bioconjugate …, 2023 - ACS Publications
Opioid use disorder (OUD) has become a public health crisis, with recent significant
increases in the number of deaths due to overdose. Vaccination can provide an attractive …

[HTML][HTML] Virus-like particles based on the novel goose parvovirus (NGPV) VP2 protein protect ducks against NGPV challenge

Y Shang, Y Ma, S Tang, X Chen, H Feng, L Li, H Wang… - Vaccines, 2023 - mdpi.com
Novel goose parvovirus (NGPV), a genetic variant of goose parvovirus, has been spreading
throughout China since 2015 and mainly infects ducklings with the symptoms of growth …

[HTML][HTML] mRNA and Adenoviral Vector Vaccine Platforms Utilized in COVID-19 Vaccines: Technologies, Ecosystem, and Future Directions

R Okuyama - Vaccines, 2023 - mdpi.com
New technological platforms, such as mRNA and adenoviral vector vaccines, have been
utilized to develop coronavirus disease 2019 (COVID-19) vaccines. These new modalities …

[HTML][HTML] Trends in COVID-19 vaccine development: Vaccine platform, developer, and nationality

R Okuyama - Vaccines, 2024 - mdpi.com
Various vaccine platforms, including emerging platforms, have been applied in the
development of COVID-19 vaccines. Biotechnology startups often lead the development of …

Bacteriophage virus-like particles: Platforms for vaccine design

E Tumban - Bacteriophages: Methods and Protocols, 2023 - Springer
Virus-like particles (VLPs) derived from bacteriophages have many applications in
biomedical sciences, especially in the development of candidate vaccines against viral and …

Vaccine adjuvants: current status, research and development, licensing, and future opportunities

Y Cui, M Ho, Y Hu, Y Shi - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Vaccines represent one of the most significant inventions in human history and have
revolutionized global health. Generally, a vaccine functions by triggering the innate immune …