Effectiveness and safety of prenatal valacyclovir for congenital cytomegalovirus infection: systematic review and meta‐analysis

F D'Antonio, D Marinceu, S Prasad… - Ultrasound in Obstetrics …, 2023 - Wiley Online Library
Objective Universal screening for cytomegalovirus (CMV) infection in pregnancy is not
recommended in most countries. One of the major deterrents is the lack of effective prenatal …

The effect of valacyclovir on secondary prevention of congenital cytomegalovirus infection, following primary maternal infection acquired periconceptionally or in the …

C Chatzakis, K Shahar-Nissan, V Faure-Bardon… - American Journal of …, 2024 - Elsevier
Objective Recent studies have shown that a dosage of 8 g/d of oral valacyclovir reduces
substantially the vertical transmission rate of cytomegalovirus in women with primary …

[HTML][HTML] Treatment with valacyclovir during pregnancy for prevention of congenital cytomegalovirus infection: a real-life multicenter Italian observational study

L Zammarchi, LR Tomasoni, G Liuzzi… - American Journal of …, 2023 - Elsevier
BACKGROUND Valacyclovir is the only treatment demonstrated to be effective for the
prevention of vertical transmission of cytomegalovirus within a clinical randomized, placebo …

New data on efficacy of valacyclovir in secondary prevention of maternal–fetal transmission of cytomegalovirus

C Egloff, J Sibiude, C Vauloup‐Fellous… - … in Obstetrics & …, 2023 - Wiley Online Library
Objective Congenital cytomegalovirus (CMV) infection is the leading cause of non‐genetic
hearing and neurological deficits. The aim of our study was to evaluate the efficacy and …

[HTML][HTML] Consensus recommendation for prenatal, neonatal and postnatal management of congenital cytomegalovirus infection from the European congenital infection …

M Leruez-Ville, C Chatzakis, D Lilleri… - The Lancet Regional …, 2024 - thelancet.com
Congenital cytomegalovirus (cCMV) infection carries a significant burden with a 0.64%
global prevalence and a 17–20% chance of serious long-term effects in children. Since the …

Pathogenesis of viral infections during pregnancy

PS Creisher, SL Klein - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
Viral infections during pregnancy are associated with significant adverse perinatal and fetal
outcomes. Pregnancy is a unique immunologic and physiologic state, which can influence …

Navigating paediatric virology through the COVID‑19 era

IN Mammas, SB Drysdale… - International …, 2023 - spandidos-publications.com
The present review article presents the key messages of the 8th Workshop on Paediatric
Virology organised virtually by the Institute of Paediatric Virology based on the island of …

[HTML][HTML] Prevention of Congenital Cytomegalovirus Infection: Review and Case Series of Valaciclovir versus Hyperimmune Globulin Therapy

G Nigro, M Muselli… - Viruses, 2023 - mdpi.com
Cytomegalovirus (CMV) is the most common cause of congenital infections in developed
countries because is capable of infecting the fetus after both primary and recurrent maternal …

[HTML][HTML] Congenital cytomegalovirus infection: the state of the art and future perspectives

S Salomè, FR Corrado, LL Mazzarelli… - Frontiers in …, 2023 - frontiersin.org
Congenital cytomegalovirus (cCMV) infection is the most common congenital infection, with
an estimated incidence of approximately one in 200 infants in high-income settings …

Serological screening for cytomegalovirus during pregnancy: A systematic review of clinical practice guidelines and consensus statements

M Xie, T Tripathi, NE Holmes, L Hui - Prenatal Diagnosis, 2023 - Wiley Online Library
Background Congenital cytomegalovirus (cCMV) is the most common congenital infection
worldwide. cCMV can lead to severe long‐term sequelae, including neurological impairment …