Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …

The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Autologous induced pluripotent stem cells (iPSCs) constitute an unlimited cell source for
patient-specific cell-based organ repair strategies. However, their generation and …

Current therapies for heart failure after myocardial infarction are limited and non-curative.
Although regenerative approaches are receiving significant attention, clinical efforts that …

Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in
vitro cell culture that has a promising future in the healthcare industry. The numerous …

Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …

Duchenne muscular dystrophy (DMD) is a severe, progressive muscle disease caused by
mutations in the dystrophin gene. The majority of DMD mutations are deletions that …

Twenty years after the initial description of a tissue engineered construct, 3-dimensional
human cardiac tissues of different kinds are now generated routinely in many laboratories …

Mitochondria are highly dynamic, except in adult cardiomyocytes. Yet, the fission and fusion-
promoting proteins that mediate mitochondrial dynamism are highly expressed in, and …

The synergism between cardiomyogenesis and angiogenesis is essential for cardiac
regeneration. Circular RNAs (circRNAs) play pivotal roles in cell growth and angiogenesis …